Volume 27, Issue 1 pp. 146-151
ORIGINAL ARTICLE

Do neutrophil–lymphocyte ratio and platelet–lymphocyte ratio have a role in determining mortality in intensive care patients undergoing plasmapheresis? Single-center experience

Sevil Sadri

Corresponding Author

Sevil Sadri

Department of Internal Medicine, Haematology, Istanbul Medipol University School of Medicine, Istanbul, Turkey

Correspondence

Sevil Sadri, Department of Internal Medicine—Haematology, Istanbul Medipol University School of Medicine, Goztepe, Metin Sk. No. 4, 34214 Bagcilar/Istanbul, Turkey.

Email: [email protected]

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Gunes Cavusoglu

Gunes Cavusoglu

Department of Internal Medicine, Haematology, Istanbul Medipol University School of Medicine, Istanbul, Turkey

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Burcu Tunay

Burcu Tunay

Department of Anesthesiology and Reanimation, Istanbul Medipol University School of Medicine, Istanbul, Turkey

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First published: 22 June 2022

Abstract

Introduction

Plasmapheresis is a frequently used procedure that removes the pathogenic components from circulation. We aimed to evaluate the relationship between plasmapheresis, neutrophil–lymphocyte ratio (NLR), platelet–lymphocyte ratio (PLR) and mortality in the intensive care unit (ICU) between 2014 and 2021.

Methods

Forty-nine patients (27 females and 22 males) were included. Demographic characteristics, laboratory values of the day of admittance to the ICU, APACHE II scores, and length of stay were recorded.

Results

The mean age was 52.73 ± 16.93. APACHE II value (p = 0.003; p < 0.01), NLR ratio (p = 0.001; p < 0.01) and PLR ratio (p = 0.001; p < 0.01) of the surviving group were lower than those of the deceased group, which was statistically significant.

Conclusion

As high PLR and NLR levels suggest increased mortality in the ICU population, attention should be paid for increased NLR and PLR when plasmapheresis is decided on in the ICU.

CONFLICT OF INTEREST

The authors declare no conflict of interest.

DATA AVAILABILITY STATEMENT

The authors agree with sharing, copying, and modifying the data used in this article, even for commercial purposes, so long as appropriate credit is given, and possible changes are indicated.

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