Reduction of E-cadherin expression in the lesion of molluscum contagiosum: A possible explanation for the lack of Langerhans cells
Tomohiro Oiwa
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan
Search for more papers by this authorCorresponding Author
Satoshi Nakamizo
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan
Correspondence
Satoshi Nakamizo, Department of Dermatology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawara-cho, Sakyo, Kyoto 606-8507, Japan.
Email: [email protected]
Search for more papers by this authorTakashi Nomura
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan
Search for more papers by this authorKaori Tomari
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan
Search for more papers by this authorYuji Horiguchi
Horiguchi Clinic of Dermatology, Hirakata, Japan
Search for more papers by this authorKenji Kabashima
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan
Search for more papers by this authorTomohiro Oiwa
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan
Search for more papers by this authorCorresponding Author
Satoshi Nakamizo
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan
Correspondence
Satoshi Nakamizo, Department of Dermatology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawara-cho, Sakyo, Kyoto 606-8507, Japan.
Email: [email protected]
Search for more papers by this authorTakashi Nomura
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan
Search for more papers by this authorKaori Tomari
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan
Search for more papers by this authorYuji Horiguchi
Horiguchi Clinic of Dermatology, Hirakata, Japan
Search for more papers by this authorKenji Kabashima
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan
Search for more papers by this authorCONFLICT OF INTEREST
None declared.
REFERENCES
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- 2Bhawan J, Dayal Y, Bhan AK. Langerhans cells in molluscum contagiosum, verruca vulgaris, plantar wart, and condyloma acuminatum. J Am Acad Dermatol. 1986; 15(4 Pt 1): 645–9.
- 3Jakob T, Udey MC. Regulation of E-cadherin-mediated adhesion in Langerhans cell-like dendritic cells by inflammatory mediators that mobilize Langerhans cells in vivo. J Immunol. 1998; 160: 4067–73.
- 4Horiguchi Y, Horiguchi J, Maeno KI. Vascular network tightly enclosing lesions of molluscum contagiosum: Basket-like capillaries of molluscum. J Dermatol. 2017; 44: 52–8.
- 5Callegaro CF, Sotto MN. Molluscum contagiosum: immunomorphological aspects of keratinocytes markers of differentiation and adhesion. J Cutan Pathol. 2009; 36: 1279–85.
