Status of microsatellite stability in angiosarcoma: Angiosarcoma is a microsatellite stable tumor
Saki Maeda-Otsuka
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorTselmeg Mijiddorj Myangat
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorCorresponding Author
Ikko Kajihara
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Correspondence
Ikko Kajihara, Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, Japan.
Email: [email protected]
Search for more papers by this authorRyoko Sakamoto
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorSaori Yamada-Kanazawa
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorSoichiro Sawamura
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorKatsunari Makino
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorShinichi Masuguchi
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorSatoshi Fukushima
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorHironobu Ihn
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Deceased 13 March 2020
Search for more papers by this authorSaki Maeda-Otsuka
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorTselmeg Mijiddorj Myangat
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorCorresponding Author
Ikko Kajihara
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Correspondence
Ikko Kajihara, Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, Japan.
Email: [email protected]
Search for more papers by this authorRyoko Sakamoto
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorSaori Yamada-Kanazawa
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorSoichiro Sawamura
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorKatsunari Makino
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorShinichi Masuguchi
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorSatoshi Fukushima
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorHironobu Ihn
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Deceased 13 March 2020
Search for more papers by this authorSaki Maeda-Otsuka and Tselmeg Mijiddorj Myangat contributed equally to this work as first author.
CONFLICT OF INTEREST
None declared.
References
- 1Florou V, Rosenberg AE, Wieder E, Komanduri KV, Kolonias D, Uduman M, et al. Angiosarcoma patients treated with immune checkpoint inhibitors: a case series of seven patients from a single institution. J Immunother Cancer. 2019; 7: 213.
- 2Le DT, Uram JN, Wang H, Bartlett BR, Kemberling H, Eyring AD, et al. PD-1 blockade in tumors with mismatch-repair deficiency. N Engl J Med. 2015; 372: 2509–20.
- 3Campanella NC, Penna V, Ribeiro G, Abrahão-Machado LF, Scapulatempo-Neto C, Reis RM, et al. Absence of microsatellite instability in soft tissue sarcomas. Pathobiology. 2015; 82: 36–42.
- 4Boichard A, Wagner MJ, Kurzrock R. Angiosarcoma heterogeneity and potential therapeutic vulnerability to immune checkpoint blockade: insights from genomic sequencing. Genome Med. 2020; 12: 61.
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