Volume 60, Issue 5 pp. o791-o792

1-[1-(trans-4-Iso­propyl­cyclo­hexyl)­piperidin-4-yl]­indolin-2-one, one of a novel series of nociceptin receptor ligands

First published: 14 May 2004
Jeffrey R. Deschamps, e-mail: [email protected]

Abstract

The title compound, C22H32N2O, is a member of the family of nociceptin receptor ligands derived from N-(4-piperidinyl)-2-indolinones. Modifications of the piperidine N-substituent can produce both agonists and antagonists, with the title compound being a weak agonist. The mol­ecule lies on a crystallographic mirror plane.

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