Crystallization and preliminary X-ray analysis of the thymidylate kinase from Mycobacterium tuberculosis
I. Li de la Sierra, e-mail: [email protected]
Abstract
Mycobacterium tuberculosis thymidylate kinase complexed with the substrate deoxythymidine monophosphate was crystallized in the hexagonal space group P6522 or P6122, with unit-cell parameters a = b = 76.62, c = 134.38 Å and one single monomer of 23 kDa in the asymmetric unit. Cryo-cooled crystals diffract at 1.94 Å resolution using synchrotron radiation.
