N-[Tris(hydroxymethyl)methyl]glycine (tricine)
Abstract
The title compound, C6H13NO5, adopts a zwitterionic form where the carboxylic acid H atom is transferred to the amino group. The methyl–glycine backbone is planar. The tris(hydroxymethyl)methyl group is rotated as a rigid group around the amino–methyl bond by 22 (1)° and the carboxylic acid plane is rotated by 19.76 (12)° from the plane of the main skeleton. Apart from their H atoms, the three hydroxymethyl groups adopt a propeller-like conformation around the amino–methyl bond, close to C3 symmetry.