Volume 57, Issue 4 pp. 421-422

N-[Tris(hydroxymethyl)methyl]glycine (tricine)

M. Ramos Silva

M. Ramos Silva

CEMDRX, Departamento de Física, Faculdade de Ciências e Tecnologia, ­Universidade de Coimbra, P-3000 Coimbra, Portugal

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J. A. Paixão

J. A. Paixão

CEMDRX, Departamento de Física, Faculdade de Ciências e Tecnologia, ­Universidade de Coimbra, P-3000 Coimbra, Portugal

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A. Matos Beja

A. Matos Beja

CEMDRX, Departamento de Física, Faculdade de Ciências e Tecnologia, ­Universidade de Coimbra, P-3000 Coimbra, Portugal

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L. Alte da Veiga

L. Alte da Veiga

CEMDRX, Departamento de Física, Faculdade de Ciências e Tecnologia, ­Universidade de Coimbra, P-3000 Coimbra, Portugal

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First published: 23 June 2004
J. A. Paixão, e-mail: [email protected]

Abstract

The title compound, C6H13NO5, adopts a zwitterionic form where the carboxylic acid H atom is transferred to the amino group. The methyl–glycine backbone is planar. The tris(hydroxy­methyl)­methyl group is rotated as a rigid group around the amino–methyl bond by 22 (1)° and the carboxylic acid plane is rotated by 19.76 (12)° from the plane of the main skeleton. Apart from their H atoms, the three hydroxy­methyl groups adopt a propeller-like conformation around the amino–methyl bond, close to C3 symmetry.

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