Documented allergies of patients with cancer
C. CHERNECKY
RN, PhD, AOCN
,
C. CHERNECKY RN, PhD, AOCN
Medical College of Georgia, Augusta, GA, USA
Search for more papers by this authorC. CHERNECKY
RN, PhD, AOCN
,
C. CHERNECKY RN, PhD, AOCN
Medical College of Georgia, Augusta, GA, USA
Search for more papers by this authorCynthia Chernecky, Medical College of Georgia, Jennings Building EB ♯220, 1115 Fifteenth Street, Augusta, GA 30912-4210, USA.
Abstract
The purpose of this study was to determine and quantify the types of allergies that occur in patients with cancer. The study sample consisted of computer-generated pharmacy records of 4510 inpatients from two oncology inpatient units over a 1-year period from a large urban hospital in the USA. Compliance with computer entry was monitored in order to ensure data accuracy. Results of the study indicate that the percentages of stated allergies for persons with cancer might be higher than those for overall populations. The top four medication allergies were penicillin, sulpha, codeine and contrast media. The top four food allergies were milk, eggs, chocolate and strawberries and the top four environmental allergies were bee stings, chemical sprays, dust and mould.
REFERENCES
- AMA Drug Evaluations Annual (1993) American Medical Association, Chicago, IL.
- Arreaza E.E. (1989) Penicillin allergy: a review. Texas Medicine 85, 36–43.
- Asselin-Poturel C., Echchakir H., Carayol G., Gay F., Opolon P., Gruenwald D., Chouaib S. & Mami-Chouaib , F. (1998) Quantitative analysis of Th1, Th2 and TGF-beta1 cytokine expression in tumor, TIL and PBL of non-small cell lung cancer patients. International Journal of Cancer 77, 7–12.
- Atkins P.C., Von Allmen C., Moskovitz A., Valenzano M. & Zweiman B. (1993) Fibrin formation during ongoing cutaneous allergic reactions: comparison of responses to antigen and codeine. Journal of Allergy and Clinical Immunology 91, 956–960.
- Bansal A.S., Bruce J., Devine P.L., Scells B. & Zimmermann P.V. (1997) Serum cytokines and tumour markers in patients with non-small cell carcinoma of the lung. Disease Markers 13, 195–199.
- Brenner A.V., Linet M.S., Fine H.A., Shapiro W.R., Selker R.G., Black P.M. & Inskip P.D. (2002) History of allergies and autoimmune diseases and risk of brain tumors in adults. International Journal of Cancer 99, 252–259.
- Chen Y.M., Yang W.K., Whang-Peng J., Tsai W.Y., Hung Y.M., Yang D.M., Lin W.C., Perng R.P. & Ting C.C. (1997) Restoration of the immunocompetence by 1L-2 activation and TCR-CD3 engagement of the in vivo anergized tumor-specific CTL from lung cancer patients. Journal of Immunology 20, 354–364.
-
Fujisawa T. &
Yamaguchi Y. (1997) Autologous tumor killing activity as a prognostic factor in primary resected nonsmall cell carcinoma of the lung.
Cancer
79, 474–481.
10.1002/(SICI)1097-0142(19970201)79:3<474::AID-CNCR8>3.0.CO;2-I CAS PubMed Web of Science® Google Scholar
- Graus F., Dalmou J., Rene R., Tora M., Malats N., Verschusren J.J., Cardenal F., Vinolas N., Garcia del Muro J., Vadell C., Mason W.P., Rosell R., Posner I.B. & Real F.X. et al. (1997) Anti-Hu antibodies in patients with small-cell lung cancer: association with complete response to therapy and improved survival. Journal of Clinical Oncology 15, 2866–2872.
- Holleb A.I., Fink D.J. & Murphy G.P. (1991) The disease state of Cancer. In: American Cancer Society Textbook of Clinical Oncology, 9–17. ACS, Atlanta, GA, USA.
- Huang M., Stolina M., Sharma S., Mao , J.T., Zhu L., Miller P.W., Woliman J., Herschman H. & Dubinett S.M. (1998) Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages. up-regulation of interleukin 10 and down-regulation of interleukin 12 production. Cancer Research 58, 1208–1216.
- Kasahara T., Sakurai Y., Amemiya M., Oguchi K. & Hisamitsu T. (1995) Suppressive effects of central opiods on delayed hypersensitivity to trinitrochlorobenezene: comparative study with morphine and electroacupuncture. In Vivo 9, 177–181.
- Korkolopoulou P., Kaldamanis L., Pezzella F., Harris A.L. & Gaffer K.C. (1996) Loss of antigen-presenting molecules (MHC class I and TAP-I) in lung cancer. British Journal of Cancer 73, 8–53.
- Kuwatsuru R., Katayama H., Tomita T., Naoi Y., Hirano A., Miyauchi T., Takeuchi N., Ozaki Y., Nakanishi A. & Sumie H. (1992) Adverse reactions to low osmolar iodine contrast media (second report). Nippon Igaku Hoshasen Gakkai Zasshi – Nippin Acta Radiologica 52, 1233–1246.
- Munjal I.D., Minna I.D., Manneckjee R., Bieck P. & Spector S.(1995) Possible role of endogenous morphine and codeine on growth regulation of lung tissue. Life Sciences 57, 517–521.
- Nambu Y., Hughes S.J., Rehemtulla A., Hamstra D., Orringer M.B. & Beer D.G. (1998) Lack of cell surface Fas/APO-1 expression in pulmonary adenocarcinoma. Journal of Clinical Investigation 101, 1102–1110.
-
Nisman B.,
Lafair J.,
Heching N.,
Lyass O.,
Baras M.,
Peretz T. &
Barak V. (1998) Evaluation of tissue polypeptide specific antigen, CYFRA 21–1, and carcinoembryonic antigen in nonsmall cell lung carcinoma: does the combined use of cytokeratin markers give any additional information?
Cancer
82, 1850–1859.
10.1002/(SICI)1097-0142(19980515)82:10<1850::AID-CNCR6>3.0.CO;2-R CAS PubMed Web of Science® Google Scholar
- Pilotti V., Mastrorill M., Pizza G., DeVinci C., Busutti L., Palareti A., Gozzetti G. & Cavallari A. (1996) Transfer factor as an adjuvant to non-small cell lung cancer (NSCLC) therapy. Biotherapy 9, 117–121.
- Rosenberg S.A. (1996) The immunotherapy of solid cancers based on cloning the genes encoding tumor-rejection antigens. Annual Review of Medicine 47, 1–91.
- Rusznak C. & Davies R.I. (1998) ABC of allergies: diagnosing allergy. British Medical Journal 316, 686–689.
- Schoolov Y.N., Pampusch M.S., Risdahl J.M., Molitor T.W. & Murtaugh M.I.P. (1995) Effect of chronic morphine treatment on immune responses to keyhole limpet hemocyanin in swine. Advances in Experimental Medicine and Biology 373, 169–174.
- Smit H.A. (2001) Chronic obstructive pulmonary disease, asthma and protective effects of food intake: from hypothesis to evidence? Respiratory Research 2, 261–264.
- Stafford C. (1988) Adverse drug reactions. Medical Times 116, 31–42.
- Stakheeva M.N. , Dizer I.A., Smol’ianinov E.S., Goldberg V.E. , Novitskii E.V., Shertoboev E.I. & Khlusova M.I. (1998) [Parameters of cellular immunity in lung cancer patients with different types of adaptation reactions during polychemotherapy] (In Russian). Voprosy Onkologii 441, 164–166.
- Surtees S.J., Stockton M.G. & Gietzen T.W. (1991) Allergy to penicillin: fable or fact? British Medical Journal 302, 1051–1052.
- Virsik P.A. & Bussiere J.L. (1995) Adjuvant effects on morphine-induced suppression of immune responses to MN rgpl2O/HIV-1 mice. Advances in Experimental Medicine and Biology 373, 183–188.
- Weynants P., Marchandise F.X. & Sibille Y. (1997) Pulmonary perspective: immunology in diagnosis and treatment of lung cancer. European Respiratory Journal 10, 1703–1719.
