Amino Acid Side-chain Hydrophobicity

Hue Sun Chan

Hue Sun Chan

University of Toronto, Toronto, Canada

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First published: 22 March 2002
Citations: 4

Abstract

Hydrophobicity is the unfavourable energetics of dissolving nonpolar compounds in water. The hydrophobicities of the 20 amino acid side-chains are currently described by hydrophobicity scales derived primarily from solubility studies; these scales have provided semiquantitative rationalizations of some properties of native (folded) proteins.

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