Ames/ Salmonella Assay: A Bacterial Test for Mutagens
James S Felton
Lawrence Livermore National Laboratory, Livermore, California, USA
Search for more papers by this authorRebekah W Wu
Lawrence Livermore National Laboratory, Livermore, California, USA
Search for more papers by this authorJames S Felton
Lawrence Livermore National Laboratory, Livermore, California, USA
Search for more papers by this authorRebekah W Wu
Lawrence Livermore National Laboratory, Livermore, California, USA
Search for more papers by this authorAbstract
The Ames/ Salmonella mutation assay is the most widely used test to determine whether chemicals can cause genetic changes (mutations) potentially leading to cancer. Chemicals related to industry, farming, foods, drugs and the environment have been discovered to be mutagens with this simple assay.
References
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Further Reading
- Tokiwa H and Ohnishi Y ( 1986 ) Mutagenicity and carcinogenicity of nitroarenes and their sources in the environment . Critical Reviews in Toxicology 17 : 23 – 60 .
- Wakabayashi K , Nagao M , Esumi H and Sugimura T ( 1992 ) Food-derived mutagens and carcinogens . Cancer Research 52 ( supplement ): 2092 s– 2098 s.
Citing Literature
