Volume 2, Issue 1 pp. 77-84
Case Report of Interest

Multiple carcinoid tumors of the gallbladder and cystic duct

Toshimitsu Ishibashi

Corresponding Author

Toshimitsu Ishibashi

Department of Surgery and Pathology, Jichi Medical School, 329-04 Minamikawachi, Tochigi, Japan

Departments of Surgery, Jichi Medical School, Minamikawachi, Tochigi, 329-04 JapanSearch for more papers by this author
Hideo Nagai

Hideo Nagai

Department of Surgery and Pathology, Jichi Medical School, 329-04 Minamikawachi, Tochigi, Japan

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Yoshikazu Yasuda

Yoshikazu Yasuda

Department of Surgery and Pathology, Jichi Medical School, 329-04 Minamikawachi, Tochigi, Japan

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Kazuhiro Furuta

Kazuhiro Furuta

Department of Surgery and Pathology, Jichi Medical School, 329-04 Minamikawachi, Tochigi, Japan

Department of Pathology, Jichi Medical School, 329-04 Minamikawachi, Tochigi, Japan

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Ken Saito

Ken Saito

Department of Pathology, Jichi Medical School, 329-04 Minamikawachi, Tochigi, Japan

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Kyotaro Kanazawa

Kyotaro Kanazawa

Department of Surgery and Pathology, Jichi Medical School, 329-04 Minamikawachi, Tochigi, Japan

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First published: 01 March 1995

Abstract

A very rare case of multiple carcinoid tumors of the gallbladder and cystic duct is reported in a 77-year-old woman. Cholecystectomy and resection of the common bile duct, with regional lymph node dissection, were performed. The tumors consisted of a large mass (30×20×15mm) in the neck of the gallbladder and three small lesions in the cystic duct. Histologically, the tumor cells were arranged in solid nests, and showed many mitoses. Histochemical studies revealed argyrophilic and argentaffinic staining. Immunohistochemically, the tumor cells were positive for serotonin, chromogranin A, Leu 7, synaptophysin, and neuron-specific enolase. Thus, the present case was diagnosed as midguttype carcinoids.

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