Monofunctional Gold Nanoparticles Prepared via a Noncovalent-Interaction-Based Solid-Phase Modification Approach†
This work is supported by the National Science Foundation CAREER award DMR 0552294 and NIRT award DMI 0506531. We thank Scott Payne at North Dakota State University for conducting the TEM analysis of our nanoparticle samples.
Graphical Abstract
Trading places: Bifunctional thiol ligands were immobilized onto positively charged silica gel and onto Rink resin through electrostatic interactions. The image shows the place-exchange reaction between the alkanethiolate-protected gold nanoparticles and the polymer-bound bifunctional thiol ligands; monocarboxyl gold nanoparticles were obtained as the major product, cleaved off from the polymer support under mild conditions.