REVIEW
Effects of curcumin consumption on human chronic diseases: A narrative review of the most recent clinical data
Maria Mantzorou,
Eleni Pavlidou,
George Vasios,
Eftychia Tsagalioti,
Constantinos Giaginis,
Corresponding Author
Maria Mantzorou
Department of Food Science and Nutrition, School of Environment, University of the Aegean, Myrina, Lemnos, Greece
Correspondence
Mantzorou Maria, PhD candidate, Department of Food Science and Nutrition, University of the Aegean, Mitropoliti Ioakim 2, Myrina, Lemnos 81440, Greece.
Email: [email protected]
Search for more papers by this authorEleni Pavlidou
Department of Food Science and Nutrition, School of Environment, University of the Aegean, Myrina, Lemnos, Greece
Search for more papers by this authorGeorge Vasios
Department of Food Science and Nutrition, School of Environment, University of the Aegean, Myrina, Lemnos, Greece
Search for more papers by this authorEftychia Tsagalioti
Department of Food Science and Nutrition, School of Environment, University of the Aegean, Myrina, Lemnos, Greece
Search for more papers by this authorConstantinos Giaginis
Department of Food Science and Nutrition, School of Environment, University of the Aegean, Myrina, Lemnos, Greece
Search for more papers by this authorMaria Mantzorou,
Eleni Pavlidou,
George Vasios,
Eftychia Tsagalioti,
Constantinos Giaginis,
Corresponding Author
Maria Mantzorou
Department of Food Science and Nutrition, School of Environment, University of the Aegean, Myrina, Lemnos, Greece
Correspondence
Mantzorou Maria, PhD candidate, Department of Food Science and Nutrition, University of the Aegean, Mitropoliti Ioakim 2, Myrina, Lemnos 81440, Greece.
Email: [email protected]
Search for more papers by this authorEleni Pavlidou
Department of Food Science and Nutrition, School of Environment, University of the Aegean, Myrina, Lemnos, Greece
Search for more papers by this authorGeorge Vasios
Department of Food Science and Nutrition, School of Environment, University of the Aegean, Myrina, Lemnos, Greece
Search for more papers by this authorEftychia Tsagalioti
Department of Food Science and Nutrition, School of Environment, University of the Aegean, Myrina, Lemnos, Greece
Search for more papers by this authorConstantinos Giaginis
Department of Food Science and Nutrition, School of Environment, University of the Aegean, Myrina, Lemnos, Greece
Search for more papers by this authorAbstract
Numerous clinical trials have investigated the potential beneficial effects of curcumin supplementation against several human chronic diseases. Up to now, it has been claimed that curcumin consumption may exert beneficial effects against several chronic diseases by promoting human health and preventing diseases. In this aspect, the present review aims to critically collect and in-depth summarize the most recent, well-designed clinical studies evaluating the potential beneficial effects of curcumin consumption on human health promotion and disease prevention. According to recent and well-designed clinical studies, curcumin consumption may benefit against obesity, metabolic syndrome, and diabetes. Moreover, curcumin consumption seems to exert a positive effect on people suffering from various types of cancer, fatty liver disease, depression, arthritis, skin diseases, gut inflammation, and symptoms of premenstrual syndrome. Due to the strong heterogeneity among the clinical studies concerning the exact effective curcumin dose and formulation, as well as the recommended treatment duration for each chronic disease, no precise and definitive conclusions could be drawn. Further large-scale prospective studies are strongly recommended, being well-designed as far as follow-up times, dosage, formulation, and duration of curcumin supplementation are concerned. Moreover, potential confounders in each specific chronic disease should carefully be taken into account in future studies.
CONFLICT OF INTEREST
The authors have declared no conflict of interest.
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