Volume 32, Issue 5 pp. 823-864
REVIEW

Medicinal uses, pharmacology, and phytochemistry of Convolvulaceae plants with central nervous system efficacies: A systematic review

Guang-Tong Chen

Guang-Tong Chen

School of Pharmacy, Nantong University, 19 Qixiu Road, Nantong, Jiangsu Province, 226001 China

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Yun Lu

Yun Lu

School of Pharmacy, Nantong University, 19 Qixiu Road, Nantong, Jiangsu Province, 226001 China

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Min Yang

Min Yang

School of Pharmacy, Nantong University, 19 Qixiu Road, Nantong, Jiangsu Province, 226001 China

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Jian-Lin Li

Corresponding Author

Jian-Lin Li

School of Pharmacy, Nantong University, 19 Qixiu Road, Nantong, Jiangsu Province, 226001 China

Correspondence

Bo-Yi Fan and Jian-Lin Li, School of Pharmacy, Nantong University, 19 Qixiu Road, Nantong, Jiangsu Province, 226001, China.

Email: [email protected]; [email protected]

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Bo-Yi Fan

Corresponding Author

Bo-Yi Fan

School of Pharmacy, Nantong University, 19 Qixiu Road, Nantong, Jiangsu Province, 226001 China

Correspondence

Bo-Yi Fan and Jian-Lin Li, School of Pharmacy, Nantong University, 19 Qixiu Road, Nantong, Jiangsu Province, 226001, China.

Email: [email protected]; [email protected]

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First published: 22 January 2018
Citations: 32

Abstract

Central nervous system (CNS) disorders play a major impact on individual lives and place a severe strain on health care resources. Convolvulaceae is a family comprising approximately 1,600–1,700 species grouped in 55–60 genera, and many species are reported to have an effect on CNS functions. A systematic review of the literature studies was carried out to summarize available evidences on Convolvulaceae plants with CNS efficacies. This review is based on various data sources such as Google Scholar, Web of Science, Scopus, PubMed, and Wanfang Data. A total of 200 related articles were included in this review. According to the research result, 54 Convolvulaceae species are suggested to display CNS efficacies historically, and 46 species have been evaluated for their CNS efficacies. In addition, 67 compounds from 16 Convolvulaceae species are recognized to possess CNS efficacies. Despite great progress made through pharmacology and phytochemistry studies on CNS active Convolvulaceae species, more exploratory research is needed to gain a better understanding of the CNS efficacies of this plant family.

CONFLICT OF INTEREST

The authors have declared that there is no conflict of interest.

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