Review
Phytochemical and Botanical Therapies for Rosacea: A Systematic Review
Whitney A. Fisk,
Hadar A. Lev-Tov,
Ashley K. Clark,
Raja K. Sivamani,
Whitney A. Fisk
Department of Dermatology, University of California—Davis, Sacramento, CA, USA
These authors contributed equally in this manuscript.Search for more papers by this authorHadar A. Lev-Tov
Department of Dermatology, Albert Einstein College of Medicine, Bronx, NY, USA
These authors contributed equally in this manuscript.Search for more papers by this authorAshley K. Clark
School of Medicine, University of California—Davis, Sacramento, CA, USA
Search for more papers by this authorCorresponding Author
Raja K. Sivamani
Department of Dermatology, University of California—Davis, Sacramento, CA, USA
Correspondence to: Raja Sivamani, MD MS CAT, Department of Dermatology, University of California—Davis, 3301 C Street, Suite 1400, Sacramento, CA, USA.
E-mail: [email protected]
Search for more papers by this authorWhitney A. Fisk,
Hadar A. Lev-Tov,
Ashley K. Clark,
Raja K. Sivamani,
Whitney A. Fisk
Department of Dermatology, University of California—Davis, Sacramento, CA, USA
These authors contributed equally in this manuscript.Search for more papers by this authorHadar A. Lev-Tov
Department of Dermatology, Albert Einstein College of Medicine, Bronx, NY, USA
These authors contributed equally in this manuscript.Search for more papers by this authorAshley K. Clark
School of Medicine, University of California—Davis, Sacramento, CA, USA
Search for more papers by this authorCorresponding Author
Raja K. Sivamani
Department of Dermatology, University of California—Davis, Sacramento, CA, USA
Correspondence to: Raja Sivamani, MD MS CAT, Department of Dermatology, University of California—Davis, 3301 C Street, Suite 1400, Sacramento, CA, USA.
E-mail: [email protected]
Search for more papers by this authorAbstract
Botanical and cosmeceutical therapies are commonly used to treat symptoms of rosacea such as facial erythema, papules/pustule counts, and telangiectasia. These products may contain plant extracts, phytochemicals, and herbal formulations. The objective of this study was to review clinical studies evaluating the use of botanical agents for the treatment of rosacea. MEDLINE and Embase databases were searched for clinical studies evaluating botanical therapies for rosacea. Major results were summarized, and study methodology was analyzed. Several botanical therapies may be promising for rosacea symptoms, but few studies are methodologically rigorous. Several plant extract and phytochemicals effectively improved facial erythema and papule/pustule counts caused by rosacea. Many studies are not methodologically rigorous. Further research is critical, as many botanicals have been evaluated in only one study. Botanical agents may reduce facial erythema and effectively improve papule/pustule counts associated with rosacea. Although promising, further research in the area is imperative. Copyright © 2015 John Wiley & Sons, Ltd.
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