A multicenter retrospective study of clinical features, laboratory characteristics, and outcomes of 166 hospitalized children with coronavirus disease 2019 (COVID-19): A preliminary report from Iranian Network for Research in Viral Diseases (INRVD)
Iraj Sedighi MD
Department of Pediatric, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
Iranian Network for Research in Viral Diseases (INRVD)
Contribution: Methodology (equal), Supervision (equal)
Search for more papers by this authorAlireza Fahimzad MD, PhD
Iranian Network for Research in Viral Diseases (INRVD)
Pediatric Infectious Diseases Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal), Methodology (equal)
Search for more papers by this authorNeda Pak MD
Iranian Network for Research in Viral Diseases (INRVD)
Children Medical Centre of Excellence, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorMitra Khalili MD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Radiology, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorMohammad R. Shokrollahi MD
Iranian Network for Research in Viral Diseases (INRVD)
Pediatric Medicine Research Center, Qom University of Medical Sciences, Qom, Iran
Contribution: Data curation (equal)
Search for more papers by this authorHosein Heydari MD
Iranian Network for Research in Viral Diseases (INRVD)
Pediatric Medicine Research Center, Qom University of Medical Sciences, Qom, Iran
Contribution: Data curation (equal)
Search for more papers by this authorZahra Movahedi MD
Iranian Network for Research in Viral Diseases (INRVD)
Pediatric Medicine Research Center, Qom University of Medical Sciences, Qom, Iran
Contribution: Data curation (equal)
Search for more papers by this authorAnahita S. Dashti MD
Iranian Network for Research in Viral Diseases (INRVD)
Alborzi Clinical Microbiology Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
Contribution: Data curation (equal)
Search for more papers by this authorFatemeh Cheraghali MD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Pediatric, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran
Contribution: Data curation (equal)
Search for more papers by this authorAhmad Shamsizadeh MD
Iranian Network for Research in Viral Diseases (INRVD)
Infectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Contribution: Data curation (equal)
Search for more papers by this authorMohammadreza Mirkarimi MD
Iranian Network for Research in Viral Diseases (INRVD)
Infectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Search for more papers by this authorMohsen Alisamir MD
Iranian Network for Research in Viral Diseases (INRVD)
Infectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Contribution: Data curation (equal)
Search for more papers by this authorHouman Hashemian MD
Iranian Network for Research in Viral Diseases (INRVD)
Pediatric Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran
Contribution: Data curation (equal)
Search for more papers by this authorJafar Soltani MD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Pediatrics, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran
Contribution: Data curation (equal)
Search for more papers by this authorAli Hosseininasab MD
Iranian Network for Research in Viral Diseases (INRVD)
Infectious and Tropical Research Center, Kerman University of Medical Sciences, Kerman, Iran
Contribution: Data curation (equal)
Search for more papers by this authorAbdolkarim Hamedi MD
Iranian Network for Research in Viral Diseases (INRVD)
Infection Control Hand and Hygiene Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Contribution: Data curation (equal)
Search for more papers by this authorMohammad S. Rezai MD
Iranian Network for Research in Viral Diseases (INRVD)
Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran
Search for more papers by this authorShirin Sayyahfar MD
Iranian Network for Research in Viral Diseases (INRVD)
Research Center of Pediatric Infectious Diseases, Institute of Immunology and Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorManijeh Kahbazi MD
Iranian Network for Research in Viral Diseases (INRVD)
Infectious Diseases Research Center (IDRC), Arak University of Medical Sciences, Arak, Iran
Contribution: Data curation (equal)
Search for more papers by this authorAliakbar Abedini MD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Pediatric Infectious Disease, Faculty of Medicine, Children, Clinical Research Development Center, Tabriz University of Medical Sciences, Tabriz, Iran
Contribution: Data curation (equal)
Search for more papers by this authorAfsaneh Akhondzadeh MD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Pediatrics, Arak University of Medical Sciences, Arak, Iran
Contribution: Data curation (equal)
Search for more papers by this authorHamid R. Sherkatolabbasieh MD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Pediatrics, Lorestan University of medical Sciences, Khorramabad, Iran
Contribution: Data curation (equal)
Search for more papers by this authorAli Akbar Razlansari MD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Pediatrics, Lorestan University of medical Sciences, Khorramabad, Iran
Contribution: Data curation (equal)
Search for more papers by this authorMina Alibeik MD
Iranian Network for Research in Viral Diseases (INRVD)
Pediatric Infectious Diseases Research Center, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorSoheil Omid Malayeri Bs
Iranian Network for Research in Viral Diseases (INRVD)
Health Clinical Sciences Research Center, Zahedan Branch, Islamic Azad University, Zahedan, Iran
Contribution: Data curation (equal)
Search for more papers by this authorZohreh Shalchi MD
Department of Pediatric, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
Iranian Network for Research in Viral Diseases (INRVD)
Contribution: Data curation (equal)
Search for more papers by this authorAli Shahabinezhad MS
Iranian Network for Research in Viral Diseases (INRVD)
Joint Reconstruction Research Center, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorParinaz K. Asl MS
Iranian Network for Research in Viral Diseases (INRVD)
International Branch, Golestsn University of Medical Sciences, Gorgan, Iran
Contribution: Validation (equal)
Search for more papers by this authorFatemeh N. Monfared MS
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Validation (equal)
Search for more papers by this authorShiva Maleki MS
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
Contribution: Validation (equal)
Search for more papers by this authorRezvan Kakavand PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
Contribution: Validation (equal)
Search for more papers by this authorMohammad Farahmand PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Formal analysis (lead)
Search for more papers by this authorBabak Shahbaz PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorAhmad Tavakoli PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Medical Virology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
Research Center of Pediatric Infectious Diseases, Institute of Immunology and Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran
Contribution: Writing - review & editing (equal)
Search for more papers by this authorSara A. Rezayat MS
Iranian Network for Research in Viral Diseases (INRVD)
Department of Health Care Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorMohammad R. Karimi BS
Iranian Network for Research in Viral Diseases (INRVD)
Department of Laboratory Sciences, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorYousef Erfani PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Laboratory Sciences, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorAli Jafarpour MS
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorSaber Soltani PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorMilad Zandi PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorAzam Ghaziasadi PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorRazieh Dowran PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorShohreh Azimi PhD
Iranian Network for Research in Viral Diseases (INRVD)
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorShima S. Marvi BS
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorMohammad F. Abazari MS
Iranian Network for Research in Viral Diseases (INRVD)
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorMehdi Norouzi PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Search for more papers by this authorIman R. Azhar MS
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorCorresponding Author
Seyed M. Jazayeri MD, PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Correspondence Seyed Mohammad Jazayeri, Department of Virology, School of Public Health, Tehran University of Medical Sciences; Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran 1417613151, Iran.
Email: [email protected]
Contribution: Funding acquisition (lead), Supervision (lead), Writing - original draft (lead), Writing - review & editing (equal)
Search for more papers by this authorIraj Sedighi MD
Department of Pediatric, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
Iranian Network for Research in Viral Diseases (INRVD)
Contribution: Methodology (equal), Supervision (equal)
Search for more papers by this authorAlireza Fahimzad MD, PhD
Iranian Network for Research in Viral Diseases (INRVD)
Pediatric Infectious Diseases Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal), Methodology (equal)
Search for more papers by this authorNeda Pak MD
Iranian Network for Research in Viral Diseases (INRVD)
Children Medical Centre of Excellence, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorMitra Khalili MD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Radiology, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorMohammad R. Shokrollahi MD
Iranian Network for Research in Viral Diseases (INRVD)
Pediatric Medicine Research Center, Qom University of Medical Sciences, Qom, Iran
Contribution: Data curation (equal)
Search for more papers by this authorHosein Heydari MD
Iranian Network for Research in Viral Diseases (INRVD)
Pediatric Medicine Research Center, Qom University of Medical Sciences, Qom, Iran
Contribution: Data curation (equal)
Search for more papers by this authorZahra Movahedi MD
Iranian Network for Research in Viral Diseases (INRVD)
Pediatric Medicine Research Center, Qom University of Medical Sciences, Qom, Iran
Contribution: Data curation (equal)
Search for more papers by this authorAnahita S. Dashti MD
Iranian Network for Research in Viral Diseases (INRVD)
Alborzi Clinical Microbiology Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
Contribution: Data curation (equal)
Search for more papers by this authorFatemeh Cheraghali MD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Pediatric, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran
Contribution: Data curation (equal)
Search for more papers by this authorAhmad Shamsizadeh MD
Iranian Network for Research in Viral Diseases (INRVD)
Infectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Contribution: Data curation (equal)
Search for more papers by this authorMohammadreza Mirkarimi MD
Iranian Network for Research in Viral Diseases (INRVD)
Infectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Search for more papers by this authorMohsen Alisamir MD
Iranian Network for Research in Viral Diseases (INRVD)
Infectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Contribution: Data curation (equal)
Search for more papers by this authorHouman Hashemian MD
Iranian Network for Research in Viral Diseases (INRVD)
Pediatric Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran
Contribution: Data curation (equal)
Search for more papers by this authorJafar Soltani MD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Pediatrics, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran
Contribution: Data curation (equal)
Search for more papers by this authorAli Hosseininasab MD
Iranian Network for Research in Viral Diseases (INRVD)
Infectious and Tropical Research Center, Kerman University of Medical Sciences, Kerman, Iran
Contribution: Data curation (equal)
Search for more papers by this authorAbdolkarim Hamedi MD
Iranian Network for Research in Viral Diseases (INRVD)
Infection Control Hand and Hygiene Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Contribution: Data curation (equal)
Search for more papers by this authorMohammad S. Rezai MD
Iranian Network for Research in Viral Diseases (INRVD)
Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran
Search for more papers by this authorShirin Sayyahfar MD
Iranian Network for Research in Viral Diseases (INRVD)
Research Center of Pediatric Infectious Diseases, Institute of Immunology and Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorManijeh Kahbazi MD
Iranian Network for Research in Viral Diseases (INRVD)
Infectious Diseases Research Center (IDRC), Arak University of Medical Sciences, Arak, Iran
Contribution: Data curation (equal)
Search for more papers by this authorAliakbar Abedini MD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Pediatric Infectious Disease, Faculty of Medicine, Children, Clinical Research Development Center, Tabriz University of Medical Sciences, Tabriz, Iran
Contribution: Data curation (equal)
Search for more papers by this authorAfsaneh Akhondzadeh MD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Pediatrics, Arak University of Medical Sciences, Arak, Iran
Contribution: Data curation (equal)
Search for more papers by this authorHamid R. Sherkatolabbasieh MD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Pediatrics, Lorestan University of medical Sciences, Khorramabad, Iran
Contribution: Data curation (equal)
Search for more papers by this authorAli Akbar Razlansari MD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Pediatrics, Lorestan University of medical Sciences, Khorramabad, Iran
Contribution: Data curation (equal)
Search for more papers by this authorMina Alibeik MD
Iranian Network for Research in Viral Diseases (INRVD)
Pediatric Infectious Diseases Research Center, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorSoheil Omid Malayeri Bs
Iranian Network for Research in Viral Diseases (INRVD)
Health Clinical Sciences Research Center, Zahedan Branch, Islamic Azad University, Zahedan, Iran
Contribution: Data curation (equal)
Search for more papers by this authorZohreh Shalchi MD
Department of Pediatric, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
Iranian Network for Research in Viral Diseases (INRVD)
Contribution: Data curation (equal)
Search for more papers by this authorAli Shahabinezhad MS
Iranian Network for Research in Viral Diseases (INRVD)
Joint Reconstruction Research Center, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorParinaz K. Asl MS
Iranian Network for Research in Viral Diseases (INRVD)
International Branch, Golestsn University of Medical Sciences, Gorgan, Iran
Contribution: Validation (equal)
Search for more papers by this authorFatemeh N. Monfared MS
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Validation (equal)
Search for more papers by this authorShiva Maleki MS
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
Contribution: Validation (equal)
Search for more papers by this authorRezvan Kakavand PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
Contribution: Validation (equal)
Search for more papers by this authorMohammad Farahmand PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Formal analysis (lead)
Search for more papers by this authorBabak Shahbaz PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorAhmad Tavakoli PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Medical Virology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
Research Center of Pediatric Infectious Diseases, Institute of Immunology and Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran
Contribution: Writing - review & editing (equal)
Search for more papers by this authorSara A. Rezayat MS
Iranian Network for Research in Viral Diseases (INRVD)
Department of Health Care Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorMohammad R. Karimi BS
Iranian Network for Research in Viral Diseases (INRVD)
Department of Laboratory Sciences, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorYousef Erfani PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Laboratory Sciences, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorAli Jafarpour MS
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorSaber Soltani PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorMilad Zandi PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorAzam Ghaziasadi PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorRazieh Dowran PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorShohreh Azimi PhD
Iranian Network for Research in Viral Diseases (INRVD)
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorShima S. Marvi BS
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorMohammad F. Abazari MS
Iranian Network for Research in Viral Diseases (INRVD)
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorMehdi Norouzi PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Search for more papers by this authorIman R. Azhar MS
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation (equal)
Search for more papers by this authorCorresponding Author
Seyed M. Jazayeri MD, PhD
Iranian Network for Research in Viral Diseases (INRVD)
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
Correspondence Seyed Mohammad Jazayeri, Department of Virology, School of Public Health, Tehran University of Medical Sciences; Research Center For Clinical Virology, Tehran University of Medical Sciences, Tehran 1417613151, Iran.
Email: [email protected]
Contribution: Funding acquisition (lead), Supervision (lead), Writing - original draft (lead), Writing - review & editing (equal)
Search for more papers by this authorAbstract
Background
The objectives of this study were to analyze the clinical features and laboratory profiles and risk factors associated with critical illness of children with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Methods
One hundred and sixty-six coronavirus disease 2019 (COVID-19) Iranian pediatric patients were recruited through a collaborative research network between March and May 2020. Demographics, clinical, laboratory, and radiological results were obtained from patient files.
Results
Of 166 patients, 102 (61%) and 64 (39%) were males and females, respectively. Ninety-six (57.8%) and 70 (42.2%), had moderate and severe conditions, respectively. Thirty (18%) of patients died. The common symptoms were fever (73%), cough (54%), and shortness of breath, headache decrease in neutrophil and platelet counts; increase values in lactate dehydrogenase, decrease in the blood pH and HCO3 were significantly associated with the disease severity. 54% and 56% of patients showed abnormal radiographic appearance in Chest X-ray and in chest computed tomography scan, respectively. Sixty-one (36.7%) of patients were referred to intensive care unit (ICU). The coexistence of comorbidity was the main factor associated with ICU admission, shock, arrhythmia, acute kidney injury, acute respiratory distress syndrome, acute cardiac injury, and death.
Conclusions
We describe a higher than previously recognized rate of COVID-19 mortality in Iranian pediatric patients. Epidemiological factors, such as the relatively high case fatality rate in the country and the presence of underlying diseases were the main factors for the high death rate.
CONFLICT OF INTERESTS
The authors declare that there are no conflict of interests.
Open Research
DATA AVAILABILITY STATEMENT
The data that support the findings of this study are available from the corresponding author upon reasonable request.
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