Cervical paraganglioma—A case report and review of all cases reported to the Manchester Children's Tumour Registry 1954–2004
Amarnath Challapalli MD
Department of Paediatric and Adolescent Oncology, Central Manchester and Manchester Children's University Hospital NHS Trust, Manchester, United Kingdom
Search for more papers by this authorLisa Howell MRCPCH
Department of Paediatric and Adolescent Oncology, Central Manchester and Manchester Children's University Hospital NHS Trust, Manchester, United Kingdom
Search for more papers by this authorMartin Farrier MRCPCH
Department of Paediatrics, Billinge Hospital, Wigan, Lancashire, United Kingdom
Search for more papers by this authorAnna Kelsey FRC Path
Department of Pathology, Central Manchester and Manchester Children's University Hospital NHS Trust, Manchester, United Kingdom
Search for more papers by this authorJillian Birch PhD
Department of Paediatric and Familial Cancer Research Group, Central Manchester and Manchester Children's University Hospital NHS Trust, Manchester, United Kingdom
Search for more papers by this authorCorresponding Author
Tim Eden FRCPCH
Department of Paediatric and Adolescent Oncology, Central Manchester and Manchester Children's University Hospital NHS Trust, Manchester, United Kingdom
Teenage Cancer Trust Young Oncology Unit, Christie Hospital NHS Trust, Wilmslow Road, Manchester M20 4BX, UK.===Search for more papers by this authorAmarnath Challapalli MD
Department of Paediatric and Adolescent Oncology, Central Manchester and Manchester Children's University Hospital NHS Trust, Manchester, United Kingdom
Search for more papers by this authorLisa Howell MRCPCH
Department of Paediatric and Adolescent Oncology, Central Manchester and Manchester Children's University Hospital NHS Trust, Manchester, United Kingdom
Search for more papers by this authorMartin Farrier MRCPCH
Department of Paediatrics, Billinge Hospital, Wigan, Lancashire, United Kingdom
Search for more papers by this authorAnna Kelsey FRC Path
Department of Pathology, Central Manchester and Manchester Children's University Hospital NHS Trust, Manchester, United Kingdom
Search for more papers by this authorJillian Birch PhD
Department of Paediatric and Familial Cancer Research Group, Central Manchester and Manchester Children's University Hospital NHS Trust, Manchester, United Kingdom
Search for more papers by this authorCorresponding Author
Tim Eden FRCPCH
Department of Paediatric and Adolescent Oncology, Central Manchester and Manchester Children's University Hospital NHS Trust, Manchester, United Kingdom
Teenage Cancer Trust Young Oncology Unit, Christie Hospital NHS Trust, Wilmslow Road, Manchester M20 4BX, UK.===Search for more papers by this authorAbstract
We report a 6-year-old male with left-sided ptosis, aniscoria and an initially missed slow growing left-sided neck mass, which was surgically excised when he was 9 years old and confirmed to be a paraganglioma. Seven years later he developed recurrent symptoms and was found to have a recurrence in the anterior mediastinum. We also report on all cases of cervical paragangliomas registered with the Manchester Children's Tumour Registry (MCTR) for the 50-year period 1954–2004. Paragangliomas are very rare tumours in the head and neck but should be considered in the differential diagnosis of neck masses especially when presenting with Horner syndrome. Recurrent symptoms and signs of hypertension herald recurrence. As these tumours can form part of a familial syndrome, long-term follow-up is necessary. Family members should be screened for early detection. Pediatr Blood Cancer 2007;48:112–116. © 2006 Wiley-Liss, Inc.
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