Muscle magnetic resonance imaging sensitivity does not decrease in chronic, mild, or proximal lower limb neuropathies
Nicolas Deroide MD, PhD
Physiologie Clinique-Explorations Fonctionnelles, AP-HP, Hôpital Lariboisière, 2 rue Ambroise Paré, 75010 Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorValérie Bousson MD, PhD
Radiologie Ostéo-Articulaire, AP-HP, Hôpital Lariboisière, Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorEdouard Daguet MD
Radiologie Ostéo-Articulaire, AP-HP, Hôpital Lariboisière, Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorJulien Dumurgier MD, PhD
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorSophie Ng Wing Tin MD
Physiologie Clinique-Explorations Fonctionnelles, AP-HP, Hôpital Lariboisière, 2 rue Ambroise Paré, 75010 Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorDidier Hannouche MD, PhD
Chirurgie Orthopédique, AP-HP, Hôpital Lariboisière, Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorPascal Richette MD, PhD
Rhumatologie, AP-HP, Hôpital Lariboisière, Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorJohann Beaudreuil MD, PhD
Rhumatologie, AP-HP, Hôpital Lariboisière, Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorFrédéric Lioté MD, PhD
Rhumatologie, AP-HP, Hôpital Lariboisière, Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorBernard Lévy MD, PhD
Physiologie Clinique-Explorations Fonctionnelles, AP-HP, Hôpital Lariboisière, 2 rue Ambroise Paré, 75010 Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorEric Vicaut MD, PhD
URC, AP-HP, Hôpital Lariboisière, Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorJean Denis Laredo MD
Radiologie Ostéo-Articulaire, AP-HP, Hôpital Lariboisière, Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorCorresponding Author
Nathalie Kubis MD, PhD
Physiologie Clinique-Explorations Fonctionnelles, AP-HP, Hôpital Lariboisière, 2 rue Ambroise Paré, 75010 Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Explorations Fonctionnelles Multidisciplinaires—Physiologie, AP-HP, Hôpital Lariboisière, 2 rue Ambroise Paré, 75010 Paris, FranceSearch for more papers by this authorNicolas Deroide MD, PhD
Physiologie Clinique-Explorations Fonctionnelles, AP-HP, Hôpital Lariboisière, 2 rue Ambroise Paré, 75010 Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorValérie Bousson MD, PhD
Radiologie Ostéo-Articulaire, AP-HP, Hôpital Lariboisière, Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorEdouard Daguet MD
Radiologie Ostéo-Articulaire, AP-HP, Hôpital Lariboisière, Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorJulien Dumurgier MD, PhD
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorSophie Ng Wing Tin MD
Physiologie Clinique-Explorations Fonctionnelles, AP-HP, Hôpital Lariboisière, 2 rue Ambroise Paré, 75010 Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorDidier Hannouche MD, PhD
Chirurgie Orthopédique, AP-HP, Hôpital Lariboisière, Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorPascal Richette MD, PhD
Rhumatologie, AP-HP, Hôpital Lariboisière, Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorJohann Beaudreuil MD, PhD
Rhumatologie, AP-HP, Hôpital Lariboisière, Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorFrédéric Lioté MD, PhD
Rhumatologie, AP-HP, Hôpital Lariboisière, Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorBernard Lévy MD, PhD
Physiologie Clinique-Explorations Fonctionnelles, AP-HP, Hôpital Lariboisière, 2 rue Ambroise Paré, 75010 Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorEric Vicaut MD, PhD
URC, AP-HP, Hôpital Lariboisière, Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorJean Denis Laredo MD
Radiologie Ostéo-Articulaire, AP-HP, Hôpital Lariboisière, Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Search for more papers by this authorCorresponding Author
Nathalie Kubis MD, PhD
Physiologie Clinique-Explorations Fonctionnelles, AP-HP, Hôpital Lariboisière, 2 rue Ambroise Paré, 75010 Paris, France
Université Paris Diderot Sorbonne Paris Cité, Paris, France
Explorations Fonctionnelles Multidisciplinaires—Physiologie, AP-HP, Hôpital Lariboisière, 2 rue Ambroise Paré, 75010 Paris, FranceSearch for more papers by this authorAbstract
Introduction: Muscle magnetic resonance imaging (MRI) is an innovative tool for exploring focal neuropathies. However, its usefulness in mild, proximal, or chronic lesions, when electromyography (EMG), the current “gold standard” sensitivity is inadequate, has yet to be studied. Methods: Clinical, MRI, and EMG examinations were performed in 113 muscles of 17 consecutive patients with clinically diagnosed lower limb focal neuropathies. The sensitivity and specificity of MRI and EMG were evaluated in relation to disease duration, severity, and anatomical location. Results: Muscle MRI was highly sensitive for the detection of denervated muscle, and, unlike EMG, its sensitivity did not decrease regardless of the anatomical location, duration, or severity of the neuropathy. Five MRI false positives were noted, including three in the thigh muscles. Conclusions: Muscle MRI is an alternative tool to EMG in proximal, mild, or chronic clinical diagnoses of lower limb focal neuropathies. However, it also seems prone to false-positive results, particularly in proximal muscles. Muscle Nerve, 2012
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