Volume 70, Issue 6 pp. 1491-1499
Note

Signal scaling improves the signal-to-noise ratio of measurements with segmented 2D-selective radiofrequency excitations

Jürgen Finsterbusch

Corresponding Author

Jürgen Finsterbusch

Department of Systems Neuroscience, University Medical Center Hamburg—Eppendorf, Hamburg, Germany

Neuroimage Nord, University Medical Centers Hamburg–Kiel–Lübeck, Hamburg, Germany

Correspondence to: Jürgen Finsterbusch, Ph.D., Institut für Systemische Neurowissenschaften, Geb. W34, Universitütsklinikum Hamburg-Eppendorf, 20246 Hamburg, Germany. E-mail: [email protected]Search for more papers by this author
Martin G. Busch

Martin G. Busch

Department of Systems Neuroscience, University Medical Center Hamburg—Eppendorf, Hamburg, Germany

Neuroimage Nord, University Medical Centers Hamburg–Kiel–Lübeck, Hamburg, Germany

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Peder E. Z. Larson

Peder E. Z. Larson

Department of Radiology and Biomedical Imaging, University of California—San Francisco, San Francisco, California, USA

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First published: 25 February 2013
Citations: 2

Abstract

Purpose

Segmented 2D-selective radiofrequency excitations can be used to acquire irregularly shaped target regions, e.g., in single-voxel MR spectroscopy, without involving excessive radiofrequency pulse durations. However, segments covering only outer k-space regions nominally use reduced B1 amplitudes (i.e., smaller flip angles) and yield lower signal contributions, which decreases the efficiency of the measurement. The purpose of this study was to show that applying the full flip angle for all segments and scaling down the acquired signal appropriately (signal scaling) retains the desired signal amplitude but reduces the noise level accordingly and, thus, increases the signal-to-noise ratio.

Methods

The principles and improvements of signal scaling were demonstrated with MR imaging and spectroscopy experiments at 3 T for a single-line segmentation of a blipped-planar trajectory.

Results

The observed signal-to-noise ration gain depended on the 2D-selective radiofrequency excitation's resolution, field-of-excitation, and its excitation profile and was between 40 and 500% for typical acquisition parameters.

Conclusion

Signal scaling can further improve the performance of measurements with segmented 2D-selective radiofrequency excitations, e.g., for MR spectroscopy of anatomically defined voxels. Magn Reson Med 70:1491–1499, 2013. © 2013 Wiley Periodicals, Inc.

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