Volume 51, Issue 6 pp. 1103-1107
Communication

Observation of significant signal voids in images of large biological samples at 11.1 T

Barbara L. Beck

Barbara L. Beck

The McKnight Brain Institute, University of Florida, Gainesville, Florida

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Kelly Jenkins

Kelly Jenkins

The McKnight Brain Institute, University of Florida, Gainesville, Florida

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Jim Caserta

Jim Caserta

Analog Devices, Winston Salem, North Carolina

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Kyle Padgett

Kyle Padgett

Department of Nuclear and Radiological Sciences, University of Florida, Gainesville, Florida

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Jeffrey Fitzsimmons

Jeffrey Fitzsimmons

The McKnight Brain Institute, University of Florida, Gainesville, Florida

Department of Neuroscience, University of Florida, Gainesville, Florida

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S.J. Blackband

Corresponding Author

S.J. Blackband

The McKnight Brain Institute, University of Florida, Gainesville, Florida

Department of Radiology, University of Florida, Gainesville, Florida

The Center for Structural Biology, University of Florida, Gainesville, Florida

The National High Magnetic Field Laboratory, Tallahassee, Florida

Department of Neuroscience, University of Florida, Gainesville, FL 32610===Search for more papers by this author
First published: 24 May 2004
Citations: 25

Abstract

Proton MRI of large biological samples were obtained on an 11.1 T / 40 cm instrument. Images were obtained of a fixed human brain and a large piece of fresh beef. The proton MR images demonstrate severe distortions within these conductive samples, indicative of shortened electrical wavelengths and wave behavior within the sample. These observations have significant implications with respect to the continuing evolution of MR to higher magnetic field strengths on large samples, particularly on humans. Magn Reson Med 51:1103–1107, 2004. © 2004 Wiley-Liss, Inc.

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