Analysis of textbook outcomes among patients undergoing resection of retroperitoneal sarcoma: A multi-institutional analysis of the US Sarcoma Collaborative
Jason T. Wiseman MD, MSPH
Department of Surgery, The Ohio State University, Columbus, Ohio
Search for more papers by this authorCecilia G. Ethun MD, MSc
Department of Surgery, Winship Cancer Institute, Emory University, Atlanta, Georgia
Search for more papers by this authorJordan M. Cloyd MD
Department of Surgery, The Ohio State University, Columbus, Ohio
Search for more papers by this authorRita Shelby MD
Department of Surgery, The Ohio State University, Columbus, Ohio
Search for more papers by this authorLorena Suarez-Kelly MD
Department of Surgery, The Ohio State University, Columbus, Ohio
Search for more papers by this authorThuy Tran MD
Department of Surgery, Stanford University, Stanford, California
Search for more papers by this authorGeorge Poultsides MD, MS
Department of Surgery, Stanford University, Stanford, California
Search for more papers by this authorHarveshp Mogal MD, MS
Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin
Search for more papers by this authorCallisia Clarke MD, MS
Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin
Search for more papers by this authorJennifer Tseng MD
Department of Surgery, University of Chicago Medicine, Chicago, Illinois
Search for more papers by this authorKevin K. Roggin MD
Department of Surgery, University of Chicago Medicine, Chicago, Illinois
Search for more papers by this authorKonstantinos Chouliaras MD
Department of Surgery, Wake Forest, Winston-Salem, North Carolina
Search for more papers by this authorKonstantinos Votanopoulos MD, PhD
Department of Surgery, Wake Forest, Winston-Salem, North Carolina
Search for more papers by this authorBradley Krasnick MD
Department of Surgery, Washington University, St. Louis, Missouri
Search for more papers by this authorRyan Fields MD
Department of Surgery, Washington University, St. Louis, Missouri
Search for more papers by this authorKara Vande Walle MD
Department of Surgery, University of Wisconsin Hospital and Clinics, Madison, Wisconsin
Search for more papers by this authorSean Ronnekleiv-Kelly MD
Department of Surgery, University of Wisconsin Hospital and Clinics, Madison, Wisconsin
Search for more papers by this authorJohn Harrison Howard MD
Department of Surgery, The Ohio State University, Columbus, Ohio
Search for more papers by this authorKenneth Cardona MD
Department of Surgery, Winship Cancer Institute, Emory University, Atlanta, Georgia
Search for more papers by this authorCorresponding Author
Valerie Grignol MD
Department of Surgery, The Ohio State University, Columbus, Ohio
Correspondence Valerie Grignol, MD, Division of Surgical Oncology, The Ohio State University Wexner Medical Center, 320 W 10th Avenue, M256 Starling Loving, Columbus, OH 43210.
Email: [email protected]
Search for more papers by this authorJason T. Wiseman MD, MSPH
Department of Surgery, The Ohio State University, Columbus, Ohio
Search for more papers by this authorCecilia G. Ethun MD, MSc
Department of Surgery, Winship Cancer Institute, Emory University, Atlanta, Georgia
Search for more papers by this authorJordan M. Cloyd MD
Department of Surgery, The Ohio State University, Columbus, Ohio
Search for more papers by this authorRita Shelby MD
Department of Surgery, The Ohio State University, Columbus, Ohio
Search for more papers by this authorLorena Suarez-Kelly MD
Department of Surgery, The Ohio State University, Columbus, Ohio
Search for more papers by this authorThuy Tran MD
Department of Surgery, Stanford University, Stanford, California
Search for more papers by this authorGeorge Poultsides MD, MS
Department of Surgery, Stanford University, Stanford, California
Search for more papers by this authorHarveshp Mogal MD, MS
Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin
Search for more papers by this authorCallisia Clarke MD, MS
Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin
Search for more papers by this authorJennifer Tseng MD
Department of Surgery, University of Chicago Medicine, Chicago, Illinois
Search for more papers by this authorKevin K. Roggin MD
Department of Surgery, University of Chicago Medicine, Chicago, Illinois
Search for more papers by this authorKonstantinos Chouliaras MD
Department of Surgery, Wake Forest, Winston-Salem, North Carolina
Search for more papers by this authorKonstantinos Votanopoulos MD, PhD
Department of Surgery, Wake Forest, Winston-Salem, North Carolina
Search for more papers by this authorBradley Krasnick MD
Department of Surgery, Washington University, St. Louis, Missouri
Search for more papers by this authorRyan Fields MD
Department of Surgery, Washington University, St. Louis, Missouri
Search for more papers by this authorKara Vande Walle MD
Department of Surgery, University of Wisconsin Hospital and Clinics, Madison, Wisconsin
Search for more papers by this authorSean Ronnekleiv-Kelly MD
Department of Surgery, University of Wisconsin Hospital and Clinics, Madison, Wisconsin
Search for more papers by this authorJohn Harrison Howard MD
Department of Surgery, The Ohio State University, Columbus, Ohio
Search for more papers by this authorKenneth Cardona MD
Department of Surgery, Winship Cancer Institute, Emory University, Atlanta, Georgia
Search for more papers by this authorCorresponding Author
Valerie Grignol MD
Department of Surgery, The Ohio State University, Columbus, Ohio
Correspondence Valerie Grignol, MD, Division of Surgical Oncology, The Ohio State University Wexner Medical Center, 320 W 10th Avenue, M256 Starling Loving, Columbus, OH 43210.
Email: [email protected]
Search for more papers by this authorAbstract
Background
The novel composite metric textbook outcome (TO) has increasingly been used as a quality indicator but has not been reported among patients undergoing surgical resection for retroperitoneal sarcoma (RPS) using multi-institutional collaborative data.
Methods
All patients who underwent resection for RPS between 2000 to 2016 from eight academic institutions were included. TO was defined as a patient with R0/R1 resection that discharged to home and was without transfusion, reoperation, grade ≥2 complications, hospital-stay >50th percentile, or 90-day readmission or mortality. Univariate and multivariable analyses were performed.
Results
Among 627 patients, 56.1% were female and the median age was 59 years. A minority of patients achieved a TO (34.9%). Factors associated with achieving a TO were tumor size <20 cm and low tumor grade, while ASA class ≥3, history of a prior cardiac event, resection of left colon/rectum, distal pancreatic resection, major venous resection and drain placement were associated with not achieving a TO (all P < .05). Achievement of a TO was associated with improved survival (median:12.7 vs 5.9 years, P < .01).
Conclusions
Among patients undergoing resection for RPS, failure to achieve TO is common and associated with significantly worse survival. The use of TO may inform patient expectations and serve as a measure for patient-level hospital performance.
CONFLICT OF INTERESTS
The authors declare that there are no conflict of interests.
Open Research
DATA AVAILABILITY STATEMENT
Data openly available in a public repository that issues datasets with DOIs.
Supporting Information
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| jso26136-sup-0001-Figure_1S.tiff786.1 KB | Supporting information |
| jso26136-sup-0002-Figure_2S.tiff911.1 KB | Supporting information |
| jso26136-sup-0003-Figure_2S.tiff718.9 KB | Supporting information |
| jso26136-sup-0004-supmat.docx13.2 KB | Supporting information |
Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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