A quantified risk-scoring system and rating model for postsurgical gastroparesis syndrome in gastric cancer patients
Xiao-dong Chen MD
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Search for more papers by this authorChen-chen Mao MD
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Search for more papers by this authorWei-teng Zhang MD
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Search for more papers by this authorJi Lin MD
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Search for more papers by this authorRui-sen Wu MD
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Search for more papers by this authorFeng-min Zhang BS
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Search for more papers by this authorXiang-wei Sun MD
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Search for more papers by this authorChu-huai Chi MD
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Search for more papers by this authorCorresponding Author
Xian Shen MD, PhD
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Department of Gastrointestinal Surgery, The Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Correspondence
Peng-fei Wang, MD, Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Shangcai Village, Wenzhou, Zhejiang Province, China.
Email: [email protected]
Xian Shen, PhD, Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Email: [email protected]
Search for more papers by this authorCorresponding Author
Peng-fei Wang MD
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Correspondence
Peng-fei Wang, MD, Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Shangcai Village, Wenzhou, Zhejiang Province, China.
Email: [email protected]
Xian Shen, PhD, Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Email: [email protected]
Search for more papers by this authorXiao-dong Chen MD
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Search for more papers by this authorChen-chen Mao MD
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Search for more papers by this authorWei-teng Zhang MD
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Search for more papers by this authorJi Lin MD
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Search for more papers by this authorRui-sen Wu MD
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Search for more papers by this authorFeng-min Zhang BS
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Search for more papers by this authorXiang-wei Sun MD
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Search for more papers by this authorChu-huai Chi MD
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Search for more papers by this authorCorresponding Author
Xian Shen MD, PhD
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Department of Gastrointestinal Surgery, The Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Correspondence
Peng-fei Wang, MD, Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Shangcai Village, Wenzhou, Zhejiang Province, China.
Email: [email protected]
Xian Shen, PhD, Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Email: [email protected]
Search for more papers by this authorCorresponding Author
Peng-fei Wang MD
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China
Correspondence
Peng-fei Wang, MD, Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Shangcai Village, Wenzhou, Zhejiang Province, China.
Email: [email protected]
Xian Shen, PhD, Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Email: [email protected]
Search for more papers by this authorAbstract
Background and Objectives
The study aimed to investigate the relationship between obesity and postsurgical gastroparesis syndrome (PGS), and to construct a scoring system and a risk model to identify patients at high risk.
Methods
A total of 634 patients were retrospectively analyzed. Clinical characteristics were evaluated via receiver operating characteristic (ROC) curve analysis. Logistic analysis was performed to determine the independent predictive indicators of PGS. A scoring system consisting of these indicators and a risk-rating model were constructed and evaluated via ROC curve analysis.
Results
Based on the ROC curves, the visceral fat area (VFA) cutoff value for PGS was 94.00. Logistic analysis showed that visceral obesity (VFA ≥ 94.00 cm2), the reconstruction technique, and tumor size were independent prognostic factors for PGS. The scoring system could predict PGS reliably with a high area under the ROC curve ([AUC] = 0.769). A high-risk rating had a high AUC (AUC I = 0.56, AUC II = 0.65, and AUC III = 0.77), indicating that the risk-rating model could effectively screen patients at high risk of PGS.
Conclusions
Visceral obesity defined by VFA effectively predicted PGS. Our scoring system may be a reliable instrument for identifying patients most at risk of PGS.
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