Potential in reducing scan times of HARDI by accurate correction of the cross-term in a hemispherical encoding scheme
Kuan-Hung Cho PhD
Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan
Search for more papers by this authorChun-Hung Yeh MS
Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan
Search for more papers by this authorYi-Ping Chao PhD
Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan
Search for more papers by this authorJiun-Jie Wang PhD
Institute of Medical Physics and Imaging Science, Chang Gung University, Taoyuan, Taiwan
Search for more papers by this authorCorresponding Author
Jyh-Horng Chen PhD
Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan
Jyh-Horng Chen, No. 1, Sec. 4, Roosevelt Rd., Taipei, 10617 Taiwan
Ching-Po Lin, Li-Nong St., Sec. 2, Peitou, Taipei, 155 Taiwan
Search for more papers by this authorCorresponding Author
Ching-Po Lin PhD
Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan
Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan
MRI Research Center, National Yang-Ming University, Taipei, Taiwan
Jyh-Horng Chen, No. 1, Sec. 4, Roosevelt Rd., Taipei, 10617 Taiwan
Ching-Po Lin, Li-Nong St., Sec. 2, Peitou, Taipei, 155 Taiwan
Search for more papers by this authorKuan-Hung Cho PhD
Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan
Search for more papers by this authorChun-Hung Yeh MS
Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan
Search for more papers by this authorYi-Ping Chao PhD
Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan
Search for more papers by this authorJiun-Jie Wang PhD
Institute of Medical Physics and Imaging Science, Chang Gung University, Taoyuan, Taiwan
Search for more papers by this authorCorresponding Author
Jyh-Horng Chen PhD
Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan
Jyh-Horng Chen, No. 1, Sec. 4, Roosevelt Rd., Taipei, 10617 Taiwan
Ching-Po Lin, Li-Nong St., Sec. 2, Peitou, Taipei, 155 Taiwan
Search for more papers by this authorCorresponding Author
Ching-Po Lin PhD
Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan
Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan
MRI Research Center, National Yang-Ming University, Taipei, Taiwan
Jyh-Horng Chen, No. 1, Sec. 4, Roosevelt Rd., Taipei, 10617 Taiwan
Ching-Po Lin, Li-Nong St., Sec. 2, Peitou, Taipei, 155 Taiwan
Search for more papers by this authorAbstract
Purpose
To reduce the scan time of high angular resolution diffusion imaging (HARDI) by using the hemispherical encoding scheme with the cross-term correction.
Materials and Methods
Unidirectional and 45° crossing phantoms were built to evaluate the accuracy of the fiber orientation estimation when using a hemispherical encoding scheme with and without the cross-term correction. The q-ball imaging using the spherical harmonic basis was adopted for estimation of fiber orientation. By recalculating the diffusion gradient strengths, we make the actual b value in all directions equal to the expected b value for the correction of the cross-term.
Results
The separation angles measured on the crossing phantom are 42.67° ± 1.50°, 42.75° ± 2.10°, and 42.93° ± 2.78° for cross-term-free results, for the results from the hemispherical encoding scheme with and without the cross-term correction. The angular errors in mapping the unidirectional phantom are 1.87°–2.29° and 4.01°–4.92° for the results using the hemispherical encoding scheme with and without correcting for the cross-term at different b values.
Conclusion
Using the hemispherical encoding scheme with the cross-term correction can potentially halve the scan time of HARDI and obtain accurate fiber orientation estimation simultaneously. This will be helpful in the clinical application of HARDI. J. Magn. Reson. Imaging 2009;29:1386–1394. © 2009 Wiley-Liss, Inc.
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