Volume 50, Issue 2 pp. 179-187
Article

Synthesis of Some New Heterocycles Derived from Ethyl 7-Amino-3-(3-methyl-5-oxo-1-phenyl-2-pyrazolin-4-yl)-5-aryl-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate of Biological Importance

Mohamed Salah K. Youssef

Corresponding Author

Mohamed Salah K. Youssef

Department of Chemistry, Faculty of Science, Assiut University, Assiut 71516, Egypt

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Mohamed S. Abbady

Mohamed S. Abbady

Department of Chemistry, Faculty of Science, Assiut University, Assiut 71516, Egypt

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Ragaa A. Ahmed

Ragaa A. Ahmed

Department of Chemistry, Faculty of Science, Assiut University, Assiut 71516, Egypt

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Ahmed A. Omar

Ahmed A. Omar

Department of Chemistry, Faculty of Science, Assiut University, Assiut 71516, Egypt

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First published: 20 March 2013
Citations: 6

Abstract

Ethyl 7-amino-3-(3-methyl-5-oxo-1-phenyl-2-pyrazolin-4-yl)-5-aryl-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate was synthesized by the reaction of 4-(2-aminothiazol-4-yl)-3-methyl-5-oxo-1-phenyl-2-pyrazoline with arylidene ethyl cyanoacetate and it transformed to related fused heterocyclic systems via reaction with various reagents. The biological activities of these compounds were evaluated.

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