p-TsOH-mediated, Versatile, and Efficient Approach for the Synthesis of Triazolyl-Carbazoles from Nitrovinylcarbazoles and Azide via 1, 3-Dipolar Cycloaddition
Vijay Kumar Reddy Avula
Department of Chemistry, Sri Venteswara University, Tiruprti, 517502 Andhra Pradesh, India
Centre for Chemical Sceince and Technology, IST, Jawaharlal Nehru Technological University Hyderabad, Kukatpally, 500085 Telangana, India
Search for more papers by this authorSwetha Vallela
Centre for Chemical Sceince and Technology, IST, Jawaharlal Nehru Technological University Hyderabad, Kukatpally, 500085 Telangana, India
Search for more papers by this authorJaya Shree Anireddy
Centre for Chemical Sceince and Technology, IST, Jawaharlal Nehru Technological University Hyderabad, Kukatpally, 500085 Telangana, India
Search for more papers by this authorCorresponding Author
Naga Raju Chamarthi
Department of Chemistry, Sri Venteswara University, Tiruprti, 517502 Andhra Pradesh, India
E-mail: [email protected]Search for more papers by this authorVijay Kumar Reddy Avula
Department of Chemistry, Sri Venteswara University, Tiruprti, 517502 Andhra Pradesh, India
Centre for Chemical Sceince and Technology, IST, Jawaharlal Nehru Technological University Hyderabad, Kukatpally, 500085 Telangana, India
Search for more papers by this authorSwetha Vallela
Centre for Chemical Sceince and Technology, IST, Jawaharlal Nehru Technological University Hyderabad, Kukatpally, 500085 Telangana, India
Search for more papers by this authorJaya Shree Anireddy
Centre for Chemical Sceince and Technology, IST, Jawaharlal Nehru Technological University Hyderabad, Kukatpally, 500085 Telangana, India
Search for more papers by this authorCorresponding Author
Naga Raju Chamarthi
Department of Chemistry, Sri Venteswara University, Tiruprti, 517502 Andhra Pradesh, India
E-mail: [email protected]Search for more papers by this authorAbstract
An efficient method for the synthesis of N-alkylated 3-(1-benzyl-1H-1,2,3-triazole-4-yl)-9H-carbazoles (5, 6, 7, 8, 9, 10) and 9-ethyl-3,6-di(1H-1,2,3-triazole-4-yl)-9H-carbazole (13) has been developed from nitroolefines. The effects of catalyst and solvent on these reactions have been investigated. p-TsOH-THF was found to be the best system for this reaction. Various triazolyl-carbazoles were prepared in good to excellent yields.
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