Volume 37, Issue 1 pp. 111-116
Original Article

Effect of number and ratio of positive lymph nodes in hypopharyngeal cancer

Yong-hong Hua MD, PhD

Yong-hong Hua MD, PhD

Head and Neck Cancer Center, Zhejiang Cancer Hospital, Hangzhou, China

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Qiao-ying Hu MD

Corresponding Author

Qiao-ying Hu MD

Head and Neck Cancer Center, Zhejiang Cancer Hospital, Hangzhou, China

Corresponding author: Q. Hu, Head and Neck Cancer Center, Zhejiang Cancer Hospital, Hangzhou, China. E-mail: [email protected]Search for more papers by this author
Yong-feng Piao MD

Yong-feng Piao MD

Head and Neck Cancer Center, Zhejiang Cancer Hospital, Hangzhou, China

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Qiu Tang MD, Phd

Qiu Tang MD, Phd

Head and Neck Cancer Center, Zhejiang Cancer Hospital, Hangzhou, China

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Zhen-fu Fu MD

Zhen-fu Fu MD

Head and Neck Cancer Center, Zhejiang Cancer Hospital, Hangzhou, China

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First published: 17 December 2013
Citations: 28

Abstract

Background

The number and ratio of positive lymph nodes are important prognostic factors in gastric cancer, but there is little data reported in hypopharyngeal cancer.

Methods

Medical data from 81 patients with hypopharyngeal cancer undergoing radical hypopharyngectomy and cervical lymph node dissection were reviewed.

Results

The median survival time was 84, 54, 30, and 13 months in patients with N0, N1, N2, and N3, respectively, and 84, 51, and 17 months with positive lymph node ratios (N ratio) 0, <10%, and >10%, respectively. Of the 24 N1 patients, the 20 patients that had an N ratio <10% had a better prognosis than the 4 patients with an N ratio >10%. Similar data was seen for the N2 patients. Tumor (T) classification, adjuvant therapy, and N ratio were independent prognostic factors in multivariate analysis.

Conclusion

The positive lymph node ratio is complementary to the current N classification system. © 2014 Wiley Periodicals, Inc. Head Neck 37: 111–116, 2015

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