Concise Report
Convenient Synthesis of Thioester-Substituted Oxindoles by Palladium-Catalyzed Thiocarbonylative Cyclization with Sulfonyl Chlorides as the Sulfur Source
Ren-Rui Xu,
Xiuyu Fang,
Xinxin Qi,
Xiao-Feng Wu,
Ren-Rui Xu
Department of Chemistry, Key Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province, Zhejiang Sci-Tech University, Hangzhou, Zhejiang, 310018 China
Search for more papers by this authorXiuyu Fang
Department of Chemistry, Key Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province, Zhejiang Sci-Tech University, Hangzhou, Zhejiang, 310018 China
Search for more papers by this authorCorresponding Author
Xinxin Qi
Department of Chemistry, Key Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province, Zhejiang Sci-Tech University, Hangzhou, Zhejiang, 310018 China
E-mail: [email protected]; [email protected]Search for more papers by this authorCorresponding Author
Xiao-Feng Wu
Dalian National Laboratory for Clean Energy, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, Liaoning, 116023 China
Leibniz-Institut für Katalyse e.V., Albert-Einstein-Straße 29a, Rostock, 18059 Germany
E-mail: [email protected]; [email protected]Search for more papers by this authorRen-Rui Xu,
Xiuyu Fang,
Xinxin Qi,
Xiao-Feng Wu,
Ren-Rui Xu
Department of Chemistry, Key Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province, Zhejiang Sci-Tech University, Hangzhou, Zhejiang, 310018 China
Search for more papers by this authorXiuyu Fang
Department of Chemistry, Key Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province, Zhejiang Sci-Tech University, Hangzhou, Zhejiang, 310018 China
Search for more papers by this authorCorresponding Author
Xinxin Qi
Department of Chemistry, Key Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province, Zhejiang Sci-Tech University, Hangzhou, Zhejiang, 310018 China
E-mail: [email protected]; [email protected]Search for more papers by this authorCorresponding Author
Xiao-Feng Wu
Dalian National Laboratory for Clean Energy, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, Liaoning, 116023 China
Leibniz-Institut für Katalyse e.V., Albert-Einstein-Straße 29a, Rostock, 18059 Germany
E-mail: [email protected]; [email protected]Search for more papers by this authorComprehensive Summary
A general and straightforward strategy for the synthesis of thioester-substituted oxindoles via a palladium-catalyzed thiocarbonylative cyclization process has been developed. With sulfonyl chlorides as promising sulfur source, a wide range of thioester-substituted oxindoles were obtained in moderate to high yields. Both aryl and alkyl sulfonyl chlorides were well tolerated, and Mo(CO)6 played a dual role as both a CO source and a reductant in this approach.
Supporting Information
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Appendix S1: Supporting Information |
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