Concise Report
Electrochemical Palladium-Catalyzed Intramolecular C—H Amination of 2-Amidobiaryls for Synthesis of Carbazoles
Qingqing Wang,
Xiaojing Zhang,
Pan Wang,
Xinlong Gao,
Heng Zhang,
Aiwen Lei,
Qingqing Wang
College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University, Wuhan, Hubei, 430072 China
Search for more papers by this authorXiaojing Zhang
College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University, Wuhan, Hubei, 430072 China
Search for more papers by this authorPan Wang
College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University, Wuhan, Hubei, 430072 China
Search for more papers by this authorXinlong Gao
College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University, Wuhan, Hubei, 430072 China
Search for more papers by this authorCorresponding Author
Heng Zhang
College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University, Wuhan, Hubei, 430072 China
E-mail: [email protected], [email protected]Search for more papers by this authorCorresponding Author
Aiwen Lei
College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University, Wuhan, Hubei, 430072 China
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032 China
National Research Center for Carbohydrate Synthesis, Jiangxi Normal University, Nanchang, Jiangxi, 330022 China
E-mail: [email protected], [email protected]Search for more papers by this authorQingqing Wang,
Xiaojing Zhang,
Pan Wang,
Xinlong Gao,
Heng Zhang,
Aiwen Lei,
Qingqing Wang
College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University, Wuhan, Hubei, 430072 China
Search for more papers by this authorXiaojing Zhang
College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University, Wuhan, Hubei, 430072 China
Search for more papers by this authorPan Wang
College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University, Wuhan, Hubei, 430072 China
Search for more papers by this authorXinlong Gao
College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University, Wuhan, Hubei, 430072 China
Search for more papers by this authorCorresponding Author
Heng Zhang
College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University, Wuhan, Hubei, 430072 China
E-mail: [email protected], [email protected]Search for more papers by this authorCorresponding Author
Aiwen Lei
College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University, Wuhan, Hubei, 430072 China
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032 China
National Research Center for Carbohydrate Synthesis, Jiangxi Normal University, Nanchang, Jiangxi, 330022 China
E-mail: [email protected], [email protected]Search for more papers by this authorMain observation and conclusion
The synthesis of carbazoles based on the electrochemical Pd-catalyzed intramolecular C—H amination of 2-amidobiaryls through oxidative cross coupling has been achieved under mild reaction conditions. The reaction can be carried out in undivided cell without the addition of external chemical oxidant. Besides good functional group compatibility, the desired carbazoles can be scaled up and modified easily. Compared with previous methods, this protocol affords a simple and sustainable avenue for the construction of carbazoles.
Supporting Information
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Appendix S1: Supporting Information |
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