ChemInform Abstract: Probing the Stereoselectivity of P-Glycoprotein—Synthesis, Biological Activity and Ligand Docking Studies of a Set of Enantiopure Benzopyrano[3,4-b][1,4]oxazines.
Abstract
Some of the title benzopyranooxazines and their precursors (I)/(II), e.g. (Ib), (Ic), (IIb), (IIc), and (IIIc) demonstrate significant P-glycoprotein inhibitory activity.