Heterocyclic Compounds
ChemInform Abstract: Synthesis of Dihydropyrano[3,2-e]indoles as Rotationally Restricted Phenolic Analogues of 5-Hydroxyindole—Thermal Claisen Approach versus Gold Catalysis.
First published: 28 April 2011
Abstract
The use on a gold catalyst facilitates the Claisen rearrangement/cyclization of propargyloxyindoles (I) allowing to reduce the reaction temperature from 156°C to 101°C with better yields of the condensed heterocycles (II).
