Volume 71, Issue 7 pp. 913-914
Coronary Artery Disease

Protamine usage following implantation of drug-eluting stents: A word of caution

John Cosgrave MD

John Cosgrave MD

Columbus and San Raffaele Hospitals, Milan, Italy

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Asif Qasim PhD

Asif Qasim PhD

Columbus and San Raffaele Hospitals, Milan, Italy

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Azeem Latib MD

Azeem Latib MD

Columbus and San Raffaele Hospitals, Milan, Italy

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Tiziana C. Aranzulla MD

Tiziana C. Aranzulla MD

Columbus and San Raffaele Hospitals, Milan, Italy

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Antonio Colombo MD

Corresponding Author

Antonio Colombo MD

Columbus and San Raffaele Hospitals, Milan, Italy

EMO Centro Cuore Columbus, 48 Via M. Buonarroti, 20145 Milan, ItalySearch for more papers by this author
First published: 22 May 2008
Citations: 10

Abstract

The treatment of hemorrhagic complications of percutaneous interventions with protamine is an accepted practice. Concerns exist about the increased thrombo-genicity of drugeluting stents. We report two cases of acute stent thrombosis following drug-eluting stent implantation related to Protamine administration. © 2008 Wiley-Liss, Inc.

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