Review
Phytochemicals and Biological Activities of Burdock (Arctium lappa L.) Extracts: A Review
Ariádine Reder Custodio de Souza,
Thais Latansio de Oliveira,
Pâmela Dias Fontana,
Milena Carvalho Carneiro,
Marcos Lúcio Corazza,
Iara Jose de Messias Reason,
Lorena Bavia,
Ariádine Reder Custodio de Souza
Department of Food Engineering, State University of Midwest, Alameda Élio Antonio Dalla Vecchia, 838, 85040-167 Guarapuava, Paraná, Brazil
Search for more papers by this authorThais Latansio de Oliveira
Center for Biological and Health Sciences, UniCesumar, Rua Desembargador Westphalen, 60, 84036-350 Ponta Grossa, Paraná, Brazil
Search for more papers by this authorPâmela Dias Fontana
Department of Medical Pathology, Federal University of Paraná, Rua Gen. Carneiro, 181, 80060-900 Curitiba, Paraná, Brazil
Search for more papers by this authorMilena Carvalho Carneiro
Department of Immunology, University of São Paulo, Avenida Prof. Lineu Prestes, 05508-000 São Paulo, Brazil
Search for more papers by this authorMarcos Lúcio Corazza
Department of Chemical Engineering, Federal University of Paraná, Avenida Coronel Francisco H. dos Santos, 81531-990 Curitiba, Paraná, Brazil
Search for more papers by this authorIara Jose de Messias Reason
Department of Medical Pathology, Federal University of Paraná, Rua Gen. Carneiro, 181, 80060-900 Curitiba, Paraná, Brazil
Search for more papers by this authorCorresponding Author
Lorena Bavia
Department of Cell Biology, Federal University of Paraná, Avenida Coronel Francisco H. dos Santos, 100, 19031, 81531-980 Curitiba, Paraná, Brazil
Search for more papers by this authorAriádine Reder Custodio de Souza,
Thais Latansio de Oliveira,
Pâmela Dias Fontana,
Milena Carvalho Carneiro,
Marcos Lúcio Corazza,
Iara Jose de Messias Reason,
Lorena Bavia,
Ariádine Reder Custodio de Souza
Department of Food Engineering, State University of Midwest, Alameda Élio Antonio Dalla Vecchia, 838, 85040-167 Guarapuava, Paraná, Brazil
Search for more papers by this authorThais Latansio de Oliveira
Center for Biological and Health Sciences, UniCesumar, Rua Desembargador Westphalen, 60, 84036-350 Ponta Grossa, Paraná, Brazil
Search for more papers by this authorPâmela Dias Fontana
Department of Medical Pathology, Federal University of Paraná, Rua Gen. Carneiro, 181, 80060-900 Curitiba, Paraná, Brazil
Search for more papers by this authorMilena Carvalho Carneiro
Department of Immunology, University of São Paulo, Avenida Prof. Lineu Prestes, 05508-000 São Paulo, Brazil
Search for more papers by this authorMarcos Lúcio Corazza
Department of Chemical Engineering, Federal University of Paraná, Avenida Coronel Francisco H. dos Santos, 81531-990 Curitiba, Paraná, Brazil
Search for more papers by this authorIara Jose de Messias Reason
Department of Medical Pathology, Federal University of Paraná, Rua Gen. Carneiro, 181, 80060-900 Curitiba, Paraná, Brazil
Search for more papers by this authorCorresponding Author
Lorena Bavia
Department of Cell Biology, Federal University of Paraná, Avenida Coronel Francisco H. dos Santos, 100, 19031, 81531-980 Curitiba, Paraná, Brazil
Search for more papers by this authorAbstract
Arctium lappa L., also known as burdock, is an edible wild plant which has the ability to grow in distinct environments and is considered a weed in several parts of the world. This species has great value in the biological and medical fields with its major secondary components being phenolic compounds and terpenes, substances rich in desired biological activities as antioxidant, antimicrobial, antitumor and anti-inflammatory. In addition, burdock leaves extracts have shown a modulatory effect on the complement system, which plays an important role in the development of inflammatory diseases, with an inhibitory effect on all complement pathways. Thus, natural products with those relevant activities are promising agents for healthcare applications. Therefore, the species A. lappa may represent an interesting asset for researching and developing new therapies for inflammatory afflictions.
Graphical Abstract
Conflict of interest
The authors declare no conflict of interest.
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