Correspondence on “Visible-Light-Switchable Chalcone-Flavylium Photochromic Systems in Aqueous Media”
Graphical Abstract
Recently, Bandyopadhyay and co-workers reported new chalcone photoswitches claimed to display advantageous optical and photochemical properties for potential biological applications, i.e., switching with blue, green and red light in aqueous solution. In this Correspondence, we argue that further experimental evidence is required to support the proposed design, data interpretation, and main conclusions.
Abstract
In a recent Communication in this journal, Bandyopadhyay and co-workers proposed a rational design of chalcone photoswitches that are claimed to convert into the respective flavylium cations upon irradiation with blue, green, and red light in aqueous media. Here we argue that the reported improvements on the optical/photochemical properties of the new chalcone photoswitches are not substantiated and that the proposed design and data interpretation rely on assumptions that have yet to be validated. We also identify a series of control experiments that can be performed to verify the hypotheses and better support the conclusions presented by the authors.
Conflict of Interests
The authors declare no conflict of interest.
Open Research
Data Availability Statement
Data sharing is not applicable to this article as no new data were created or analyzed in this study.
