Review
Single Molecules, Cells, and Super-Resolution Optics (Nobel Lecture)†
Eric Betzig,
Corresponding Author
Eric Betzig
Janelia Research Campus, Howard Hughes Medical Institute, 19700 Helix Dr., Ashburn, VA 20147 (USA)
Janelia Research Campus, Howard Hughes Medical Institute, 19700 Helix Dr., Ashburn, VA 20147 (USA)Search for more papers by this authorEric Betzig,
Corresponding Author
Eric Betzig
Janelia Research Campus, Howard Hughes Medical Institute, 19700 Helix Dr., Ashburn, VA 20147 (USA)
Janelia Research Campus, Howard Hughes Medical Institute, 19700 Helix Dr., Ashburn, VA 20147 (USA)Search for more papers by this author†
Copyright© The Nobel Foundation 2014. We thank the Nobel Foundation, Stockholm, for permission to print this lecture.
Graphical Abstract
The resolution of a microscope is determined by the diffraction limit in classical microscopy, whereby objects that are separated by half a wavelength can no longer be visually separated. To go below the diffraction limit required several tricks and discoveries. In his Nobel Lecture, E. Betzig describes the developments that have led to modern super high-resolution microscopy.
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