Simple and Green Synthesis of Nitrogen-Doped Photoluminescent Carbonaceous Nanospheres for Bioimaging†
Wei Li
Department of Chemistry, and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, (P. R. China) http://www.mesogroup.fudan.edu.cn/
These authors contributed equally to this work.
Search for more papers by this authorZehui Zhang
State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433 (P. R. China)
These authors contributed equally to this work.
Search for more papers by this authorBiao Kong
Department of Chemistry, and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, (P. R. China) http://www.mesogroup.fudan.edu.cn/
Search for more papers by this authorShanshan Feng
Department of Chemistry, and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, (P. R. China) http://www.mesogroup.fudan.edu.cn/
Search for more papers by this authorDr. Jinxiu Wang
Department of Chemistry, and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, (P. R. China) http://www.mesogroup.fudan.edu.cn/
Search for more papers by this authorDr. Lingzhi Wang
Department of Chemistry, and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, (P. R. China) http://www.mesogroup.fudan.edu.cn/
Search for more papers by this authorJianping Yang
Department of Chemistry, and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, (P. R. China) http://www.mesogroup.fudan.edu.cn/
Search for more papers by this authorDr. Fan Zhang
Department of Chemistry, and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, (P. R. China) http://www.mesogroup.fudan.edu.cn/
Search for more papers by this authorCorresponding Author
Prof. Dr. Peiyi Wu
State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433 (P. R. China)
Peiyi Wu, State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433 (P. R. China)
Dongyuan Zhao, Department of Chemistry, and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, (P. R. China) http://www.mesogroup.fudan.edu.cn/
Search for more papers by this authorCorresponding Author
Prof. Dr. Dongyuan Zhao
Department of Chemistry, and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, (P. R. China) http://www.mesogroup.fudan.edu.cn/
Peiyi Wu, State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433 (P. R. China)
Dongyuan Zhao, Department of Chemistry, and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, (P. R. China) http://www.mesogroup.fudan.edu.cn/
Search for more papers by this authorWei Li
Department of Chemistry, and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, (P. R. China) http://www.mesogroup.fudan.edu.cn/
These authors contributed equally to this work.
Search for more papers by this authorZehui Zhang
State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433 (P. R. China)
These authors contributed equally to this work.
Search for more papers by this authorBiao Kong
Department of Chemistry, and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, (P. R. China) http://www.mesogroup.fudan.edu.cn/
Search for more papers by this authorShanshan Feng
Department of Chemistry, and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, (P. R. China) http://www.mesogroup.fudan.edu.cn/
Search for more papers by this authorDr. Jinxiu Wang
Department of Chemistry, and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, (P. R. China) http://www.mesogroup.fudan.edu.cn/
Search for more papers by this authorDr. Lingzhi Wang
Department of Chemistry, and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, (P. R. China) http://www.mesogroup.fudan.edu.cn/
Search for more papers by this authorJianping Yang
Department of Chemistry, and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, (P. R. China) http://www.mesogroup.fudan.edu.cn/
Search for more papers by this authorDr. Fan Zhang
Department of Chemistry, and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, (P. R. China) http://www.mesogroup.fudan.edu.cn/
Search for more papers by this authorCorresponding Author
Prof. Dr. Peiyi Wu
State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433 (P. R. China)
Peiyi Wu, State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433 (P. R. China)
Dongyuan Zhao, Department of Chemistry, and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, (P. R. China) http://www.mesogroup.fudan.edu.cn/
Search for more papers by this authorCorresponding Author
Prof. Dr. Dongyuan Zhao
Department of Chemistry, and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, (P. R. China) http://www.mesogroup.fudan.edu.cn/
Peiyi Wu, State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433 (P. R. China)
Dongyuan Zhao, Department of Chemistry, and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, (P. R. China) http://www.mesogroup.fudan.edu.cn/
Search for more papers by this authorThis work was supported by the State Key Basic Research Program of the PRC (2012CB224805, 2013CB934104), and the NSF of China (21210004).
Graphical Abstract
From silk to spheres: A large-scale synthesis of water-soluble nitrogen-doped polymer-like carbonaceous nanospheres with a uniform size of ca. 70 nm, through a simple and green hydrothermal process employing cocoon silk in water, has been developed. The resultant nanospheres show excellent photoluminescent properties, exhibit low toxicity, and are biocompatible for in vivo imaging.
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References
- 1L. Dai, Angew. Chem. 2011, 123, 4840; Angew. Chem. Int. Ed. 2011, 50, 4744.
- 2M. Prato, J. Mater. Chem. 1997, 7, 1097.
- 3J. Liang, Y. Jiao, M. Jaroniec, S. Z. Qiao, Angew. Chem. 2012, 124, 11664; Angew. Chem. Int. Ed. 2012, 51, 11496.
- 4
- 4aW. Li, F. Zhang, Y. Q. Dou, Z. X. Wu, H. J. Liu, X. F. Qian, D. Gu, Y. Y. Xia, B. Tu, D. Y. Zhao, Adv. Energy Mater. 2011, 1, 382;
- 4bW. Li, D. Y. Zhao, Chem. Commun. 2013, 49, 943.
- 5
- 5aL. Cao, M. J. Meziani, S. Sahu, Y. P. Sun, Acc. Chem. Res. 2013, 46, 171;
- 5bS. N. Baker, G. A. Baker, Angew. Chem. 2010, 122, 6876; Angew. Chem. Int. Ed. 2010, 49, 6726;
- 5cH. Li, Z. Kang, Y. Liu, S.-T. Lee, J. Mater. Chem. 2012, 22, 24230.
- 6
- 6aP. W. Barone, S. Baik, D. A. Heller, M. S. Strano, Nat. Mater. 2005, 4, 86;
- 6bX. Michalet, F. F. Pinaud, L. A. Bentolila, J. M. Tsay, S. Doose, J. J. Li, G. Sundaresan, A. M. Wu, S. S. Gambhir, S. Weiss, Science 2005, 307, 538;
- 6cU. Resch-Genger, M. Grabolle, S. Cavaliere-Jaricot, R. Nitschke, T. Nann, Nat. Methods 2008, 5, 763.
- 7
- 7aL. Cao, X. Wang, M. J. Meziani, F. S. Lu, H. F. Wang, P. J. G. Luo, Y. Lin, B. A. Harruff, L. M. Veca, D. Murray, S. Y. Xie, Y. P. Sun, J. Am. Chem. Soc. 2007, 129, 11318;
- 7bD. Y. Pan, J. C. Zhang, Z. Li, M. H. Wu, Adv. Mater. 2010, 22, 734;
- 7cR. L. Liu, D. Q. Wu, X. L. Feng, K. Mullen, J. Am. Chem. Soc. 2011, 133, 15221.
- 8X. Y. Xu, R. Ray, Y. L. Gu, H. J. Ploehn, L. Gearheart, K. Raker, W. A. Scrivens, J. Am. Chem. Soc. 2004, 126, 12736.
- 9S.-L. Hu, K.-Y. Niu, J. Sun, J. Yang, N.-Q. Zhao, X.-W. Du, J. Mater. Chem. 2009, 19, 484.
- 10
- 10aH. T. Li, X. D. He, Z. H. Kang, H. Huang, Y. Liu, J. L. Liu, S. Y. Lian, C. H. A. Tsang, X. B. Yang, S. T. Lee, Angew. Chem. 2010, 122, 4532; Angew. Chem. Int. Ed. 2010, 49, 4430;
- 10bJ. G. Zhou, C. Booker, R. Y. Li, X. T. Zhou, T. K. Sham, X. L. Sun, Z. F. Ding, J. Am. Chem. Soc. 2007, 129, 744.
- 11
- 11aH. P. Liu, T. Ye, C. D. Mao, Angew. Chem. 2007, 119, 6593; Angew. Chem. Int. Ed. 2007, 46, 6473;
- 11bR. L. Liu, D. Q. Wu, S. H. Liu, K. Koynov, W. Knoll, Q. Li, Angew. Chem. 2009, 121, 4668; Angew. Chem. Int. Ed. 2009, 48, 4598.
- 12
- 12aJ. Wang, C.-F. Wang, S. Chen, Angew. Chem. 2012, 124, 9431; Angew. Chem. Int. Ed. 2012, 51, 9297;
- 12bS. Qu, X. Wang, Q. Lu, X. Liu, L. Wang, Angew. Chem. 2012, 124, 12381; Angew. Chem. Int. Ed. 2012, 51, 12215.
- 13
- 13aB. Kong, A. W. Zhu, C. Q. Ding, X. M. Zhao, B. Li, Y. Tian, Adv. Mater. 2012, 24, 5844;
- 13bA. W. Zhu, Q. Qu, X. L. Shao, B. Kong, Y. Tian, Angew. Chem. 2012, 124, 7297; Angew. Chem. Int. Ed. 2012, 51, 7185.
- 14
- 14aS. Zhu, Q. Meng, L. Wang, J. Zhang, Y. Song, H. Jin, K. Zhang, H. Sun, H. Wang, B. Yang, Angew. Chem. 2013, 125, 4045; Angew. Chem. Int. Ed. 2013, 52, 3953;
- 14bS. Liu, J. Tian, L. Wang, Y. Zhang, X. Qin, Y. Luo, A. M. Asiri, A. O. Al-Youbi, X. Sun, Adv. Mater. 2012, 24, 2037;
- 14cC. Z. Zhu, J. F. Zhai, S. J. Dong, Chem. Commun. 2012, 48, 9367;
- 14dY. Li, Y. Zhao, H. H. Cheng, Y. Hu, G. Q. Shi, L. M. Dai, L. T. Qu, J. Am. Chem. Soc. 2012, 134, 15.
- 15
- 15aM.-M. Titirici, M. Antonietti, Chem. Soc. Rev. 2010, 39, 103;
- 15bB. Hu, K. Wang, L. Wu, S.-H. Yu, M. Antonietti, M.-M. Titirici, Adv. Mater. 2010, 22, 813.
- 16Y. S. Yun, S. Y. Cho, J. Shim, B. H. Kim, S.-J. Chang, S. J. Baek, Y. S. Huh, Y. Tak, Y. W. Park, S. Park, H.-J. Jin, Adv. Mater. 2013, 25, 1993.
- 17
- 17aH. J. Jin, J. Park, V. Karageorgiou, U. J. Kim, R. Valluzzi, P. Cebe, D. L. Kaplan, Adv. Funct. Mater. 2005, 15, 1241;
- 17bR. Nazarov, H. J. Jin, D. L. Kaplan, Biomacromolecules 2004, 5, 718.
- 18D. M. Phillips, L. F. Drummy, D. G. Conrady, D. M. Fox, R. R. Naik, M. O. Stone, P. C. Trulove, H. C. De Long, R. A. Mantz, J. Am. Chem. Soc. 2004, 126, 14350.
- 19
- 19aP. Valle-Vigón, M. Sevilla, A. B. Fuertes, Chem. Mater. 2010, 22, 2526;
- 19bY. Hu, J. Ge, Y. Sun, T. Zhang, Y. Yin, Nano Lett. 2007, 7, 1832.
- 20M. J. Bojdys, J.-O. Müller, M. Antonietti, A. Thomas, Chem. Eur. J. 2008, 14, 8177.
- 21Y. Zheng, Y. Jiao, L. Ge, M. Jaroniec, S. Z. Qiao, Angew. Chem. 2013, 125, 3192; Angew. Chem. Int. Ed. 2013, 52, 3110.
- 22A. T. Quitain, H. Daimon, K. Fujie, S. Katoh, T. Moriyoshi, Ind. Eng. Chem. Res. 2006, 45, 4471.
- 23Y. H. Yang, Z. Z. Shao, X. Chen, P. Zhou, Biomacromolecules 2004, 5, 773.
