Peter J. Sadler

First published: 20 February 2013

https://doi.org/10.1002/anie.201209484

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“My biggest motivation is the excitement of discovery. My favorite piece of research is a discovery that you had not intended to make in the first place …︁” This and more about Peter J. Sadler can be found on page 6136.

References

1“Organometallic Ruthenium and Iridium Transfer-Hydrogenation Catalysts Using Coenzyme NADH as a Cofactor”: S. Betanzos-Lara, Z. Liu, A. Habtemariam, A. M. Pizarro, B. Qamar, P. J. Sadler, Angew. Chem. 2012, 124, 3963–3966;
10.1002/ange.201108175
Google Scholar
Angew. Chem. Int. Ed. 2012, 51, 3897–3900. (Can organometallic anticancer complexes form hydride complexes in cells?)
10.1002/anie.201108175
CAS PubMed Web of Science® Google Scholar
2“A potent Trans-Diimine Platinum Anticancer Complex Photoactivated by Visible Light”: N. J. Farrer, J. A. Woods, L. Salassa, Y. Zhao, K. S. Robinson, G. Clarkson, F. S. Mackay, P. J. Sadler, Angew. Chem. 2010, 122, 9089–9092;
10.1002/ange.201003399
Google Scholar
Angew. Chem. Int. Ed. 2010, 49, 8905–8908. (Excited-state drugs offer the prospect of novel mechanisms of action and fewer side-effects.)
10.1002/anie.201003399
CAS PubMed Web of Science® Google Scholar
3“Inhibition of Cancer Cell Growth by Ruthenium(II) Arene Complexes”: R. E. Morris, R. E. Aird, P. del S. Murdoch, H. Chen, J. Cummings, N. D. Hughes, S. Parsons, A. Parkin, G. Boyd, D. I. Jodrell, P. J. Sadler, J. Med. Chem. 2001, 44, 3616–3621. (Half-sandwich organometallic complexes offer a rich platform for drug design.)
10.1021/jm010051m
CAS PubMed Web of Science® Google Scholar
4“Highly Selective Binding of Organometallic Ruthenium Ethylenediamine Complexes to Nucleic Acids: Novel Recognition Mechanisms”: H. Chen, J. A. Parkinson, R. E. Morris, P. J. Sadler, J. Am. Chem. Soc. 2003, 125, 173–186. (Both the metal and the ligands can play major roles in the recognition of target sites for metallodrugs.)
10.1021/ja027719m
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5“Interdomain zinc site on human albumin”: A. J. Stewart, C. A. Blindauer, S. Berezenko, D. Sleep, P. J. Sadler, Proc. Natl. Acad. Sci. USA 2003, 100, 3701–3706. (An insight into how zinc is transported by albumin in blood.)
10.1073/pnas.0436576100
CAS PubMed Web of Science® Google Scholar

Volume52, Issue24

June 10, 2013

Page 6136

Peter J. Sadler

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