One-Step Emulsification of Multiple Concentric Shells with Capillary Microfluidic Devices†
Dr. Shin-Hyun Kim
School of Engineering and Applied Sciences, Department of Physics, Harvard University, Cambridge, MA 02138 (USA) http://weitzlab.seas.harvard.edu/
Search for more papers by this authorCorresponding Author
Prof. David A. Weitz
School of Engineering and Applied Sciences, Department of Physics, Harvard University, Cambridge, MA 02138 (USA) http://weitzlab.seas.harvard.edu/
School of Engineering and Applied Sciences, Department of Physics, Harvard University, Cambridge, MA 02138 (USA) http://weitzlab.seas.harvard.edu/Search for more papers by this authorDr. Shin-Hyun Kim
School of Engineering and Applied Sciences, Department of Physics, Harvard University, Cambridge, MA 02138 (USA) http://weitzlab.seas.harvard.edu/
Search for more papers by this authorCorresponding Author
Prof. David A. Weitz
School of Engineering and Applied Sciences, Department of Physics, Harvard University, Cambridge, MA 02138 (USA) http://weitzlab.seas.harvard.edu/
School of Engineering and Applied Sciences, Department of Physics, Harvard University, Cambridge, MA 02138 (USA) http://weitzlab.seas.harvard.edu/Search for more papers by this authorThis work was supported by Amore-Pacific, the NSF (DMR-1006546) and the Harvard MRSEC (DMR-0820484).
Graphical Abstract
Polymere Zwiebel: Ein einfaches Herstellungsverfahren für mehrphasige monodisperse Emulsionstropfen in einem Mikrofluidiksystem wurde entwickelt. Die Tropfen entstehen beim Eingrenzen coaxialer Mehrphasenströme in Mikrokapillaren. Das durch den Kerntropfen ausgelöste Aufbrechen der Phasengrenzflächen führt zu Emulsionstropfen mit zwiebelschalenartigem Aufbau.
Supporting Information
Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors.
| Filename | Description |
|---|---|
| ange_201102946_sm_anie.201102946_movie_s1.mov3.2 MB | anie.201102946_movie_s1 |
| ange_201102946_sm_anie.201102946_movie_s2.mov1.1 MB | anie.201102946_movie_s2 |
| ange_201102946_sm_anie.201102946_movie_s3.mov3.7 MB | anie.201102946_movie_s3 |
| ange_201102946_sm_anie.201102946_movie_s4.mov2.6 MB | anie.201102946_movie_s4 |
| ange_201102946_sm_miscellaneous_information.pdf1.6 MB | miscellaneous_information |
Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
References
- 1
- 1aL. Y. Chu, A. S. Utada, R. K. Shah, J. W. Kim, D. A. Weitz, Angew. Chem. 2007, 119, 9128–9132; Angew. Chem. Int. Ed. 2007, 46, 8970–8974;
- 1bJ. U. Shim, G. Cristobal, D. R. Link, T. Thorsen, Y. W. Jia, K. Piattelli, S. Fraden, J. Am. Chem. Soc. 2007, 129, 8825–8835.
- 2
- 2aS. Okushima, T. Nisisako, T. Torii, T. Higuchi, Langmuir 2004, 20, 9905–9908;
- 2bA. S. Utada, E. Lorenceau, D. R. Link, P. D. Kaplan, H. A. Stone, D. A. Weitz, Science 2005, 308, 537–541.
- 3
- 3aD. K. Hwang, D. Dendukuri, P. S. Doyle, Lab Chip 2008, 8, 1640–1647;
- 3bS.-H. Kim, S.-J. Jeon, W. C. Jeong, H. S. Park, S.-M. Yang, Adv. Mater. 2008, 20, 4129–4134;
- 3cZ. H. Nie, W. Li, M. Seo, S. Q. Xu, E. Kumacheva, J. Am. Chem. Soc. 2006, 128, 9408–9412;
- 3dS. Xu, Z. Nie, M. Seo, P. Lewis, E. Kumacheva, H. A. Stone, P. Garstecki, D. B. Weibel, I. Gitlin, G. M. Whitesides, Angew. Chem. Int. Ed. 2005, 44, 3799–3799; e) S.-H. Kim, A. Abbaspourrad, D. A. Weitz, J. Am. Chem. Soc. 2011, 133, 5516–5524.
- 4
- 4aS. W. Choi, Y. Zhang, Y. N. Xia, Adv. Funct. Mater. 2009, 19, 2943–2949;
- 4bJ. W. Kim, A. S. Utada, A. Fernandez-Nieves, Z. B. Hu, D. A. Weitz, Angew. Chem. 2007, 119, 1851–1854; Angew. Chem. Int. Ed. 2007, 46, 1819–1822;
- 4cS.-H. Kim, S.-J. Jeon, S.-M. Yang, J. Am. Chem. Soc. 2008, 130, 6040–6046;
- 4dD. Lee, D. A. Weitz, Adv. Mater. 2008, 20, 3498–3503;
- 4eH. C. Shum, J. W. Kim, D. A. Weitz, J. Am. Chem. Soc. 2008, 130, 9543–9549.
- 5A. R. Abate, D. A. Weitz, Small 2009, 5, 2030–2032.
- 6
- 6aP. Guillot, A. Colin, A. Ajdari, Phys. Rev. E 2008, 78, 016307;
- 6bP. Guillot, A. Colin, A. S. Utada, A. Ajdari, Phys. Rev. Lett. 2007, 99, 104502.
- 7A. S. Utada, A. Fernandez-Nieves, H. A. Stone, D. A. Weitz, Phys. Rev. Lett. 2007, 99, 094502.
- 8
- 8aB. Comiskey, J. D. Albert, H. Yoshizawa, J. Jacobson, Nature 1998, 394, 253–255;
- 8bN. K. Sheridon, M. A. Berkovitz, P. Sid. 1977, 18, 289–293.
- 9
- 9aD. Lane, Nat. Biotechnol. 2006, 24, 163–164;
- 9bT. P. Richardson, M. C. Peters, A. B. Ennett, D. J. Mooney, Nat. Biotechnol. 2001, 19, 1029–1034.
Citing Literature
This is the
German version
of Angewandte Chemie.
Note for articles published since 1962:
Do not cite this version alone.
Take me to the International Edition version with citable page numbers, DOI, and citation export.
We apologize for the inconvenience.
