Volume 13, Issue 10 pp. 1982-1986
RESEARCH NOTE

Post-irradiation nasal nitric oxide in patients with nasopharyngeal carcinoma

Yan-Ting Ho MD

Yan-Ting Ho MD

Department of Otolaryngology, Head and Neck Surgery, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan

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Ta-Jen Lee MD

Ta-Jen Lee MD

Department of Otolaryngology, Head and Neck Surgery, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan

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Po-Hung Chang MD

Po-Hung Chang MD

Department of Otolaryngology, Head and Neck Surgery, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan

Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan

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Chia-Hsiang Fu MD, PhD

Corresponding Author

Chia-Hsiang Fu MD, PhD

Department of Otolaryngology, Head and Neck Surgery, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan

Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan

Correspondence

Chia-Hsiang Fu, MD, PhD, Division of Rhinology, Department of Otolaryngology, Chang Gung Memorial Hospital and Chang Gung University, 5 Fu-Shin Street, Guishan, Taoyuan 333, Taiwan.

Email: [email protected]

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First published: 25 March 2023

Abstract

Key Points

  • nNO levels decreased at 3 and 6 months and recovered at 12 months after radiotherapy in NPC.
  • nNO may be a feasible biomarker for mucociliary function in post-irradiated NPC patients.
  • Lower nNO levels were associated with more sinonasal burdens in post-irradiated NPC patients.

CONFLICT OF INTEREST STATEMENT

The authors declare no conflicts of interest.

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