Accelerated Failure-time Models

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Ian James

Ian James

Murdoch University, Perth, Western Australia, Australia

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First published: 15 July 2005

Abstract

The accelerated failure-time model assumes a survival function of the form S(t) = S0t), where S0 is an underlying survival function and θ may depend on a number of covariates. This is equivalent to a location-shift model for the log failure time, and in particular to a loglinear regression model when θ is loglinear. Parametric and semiparametric approaches to analyses based on these models with possibly censored failure-time responses are reviewed. The accelerated failure-time assumption is compared and contrasted with that of proportional hazards.

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