Epstein‐Barr Virus and Cytomegalovirus - Manual of Molecular and Clinical Laboratory Immunology - Wiley Online Library

Epstein-Barr virus (EBV; also known as human herpesvirus 4 [HHV-4]) and cytomegalovirus (CMV; also known as HHV-5) logically belong in the same chapter. Both of these human herpesviruses are major pathogens for the immunocompromised host, and both are capable of causing disease during primary infection, reactivation, or superinfection. They, along with BK polyomavirus, are the feared viral triumvirate that complicates hematopoietic cell transplantation (HCT) or solid organ transplantation. This chapter emphasizes recognition of EBV and CMV diseases and focuses on the clinical relevance of laboratory findings.

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