Volume 21, Issue 3 pp. 346-362
Original Article

Skin colour, skin redness and melanin biometric measurements: comparison study between Antera® 3D, Mexameter® and Colorimeter®

Ana Rita Matias

Corresponding Author

Ana Rita Matias

Inovapotek, Pharmaceutical Research & Development, Porto, Portugal

Address:

Ana Rita Batista Matias

UPTEC

Rua Alfredo Allen, nr. 455/461

4200-135 Porto - Portugal

Tel: +351 220301531

Fax: +351 220301532

e-mail: [email protected]

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Marta Ferreira

Marta Ferreira

Inovapotek, Pharmaceutical Research & Development, Porto, Portugal

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Paulo Costa

Paulo Costa

Faculty of Pharmacy of University of Porto, Porto, Portugal

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Patrícia Neto

Patrícia Neto

Inovapotek, Pharmaceutical Research & Development, Porto, Portugal

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First published: 03 February 2015
Citations: 134

Abstract

Background

The actual skin colorimeters analyse reflect values from a limited number of broad spectral bands and consequently present limited reproducibility and specificity when measuring skin colour. Here, Antera 3D®, a new device which uses reflectance mapping of seven different light wavelengths spanning the entire visible spectrum, has been compared with Mexameter® MX-18, an established narrow-band reflectance spectrophotometer and with Colorimeter® CL-400, an established tristimulus colorimetric instrument.

Methods

Thirty volunteers were exposed to a controlled ultra-violet B light. Measurements with Antera 3D®, Mexameter® MX-18 and Colorimeter® CL-400 were done before treatment and after 2, 7 and 14 days.

Results

Antera 3D® showed to have a better sensitivity and specificity than Mexameter® MX-18 regarding the melanin parameter. A similar sensitivity between Antera 3D® and Mexameter® MX-18 was found for erythema determination and also for the Commission Internationale de l'Eclairage L*, a* and b* parameters between Antera 3D® and Colorimeter® CL-400. Good correlations were observed for all the parameters analysed. Repeatability of Mexameter® MX-18 and Colorimeter® CL-400 values were lower than that of Antera 3D® for all the parameters analysed.

Conclusion

Antera 3D®, such as Mexameter® MX-18 and Colorimeter® CL-400, are robust, sensitive and precise equipment for the skin colour analysis.

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