Volume 28, Issue 3 e14744
ORIGINAL ARTICLE

Kidney transplant in pediatric gut transplant recipients – Technical challenges and outcomes

Arpit Amin

Arpit Amin

Department of Surgery, Hillman Center for Pediatric Transplantation and Thomas E. Starzl Transplantation Institute, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA

Search for more papers by this author
Bishoy Emmanuel

Bishoy Emmanuel

Department of Surgery, Hillman Center for Pediatric Transplantation and Thomas E. Starzl Transplantation Institute, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA

Search for more papers by this author
Vikram Raghu

Vikram Raghu

Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA

Search for more papers by this author
Ajai Khanna

Ajai Khanna

Department of Surgery, Hillman Center for Pediatric Transplantation and Thomas E. Starzl Transplantation Institute, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA

Search for more papers by this author
Kyle Soltys

Kyle Soltys

Department of Surgery, Hillman Center for Pediatric Transplantation and Thomas E. Starzl Transplantation Institute, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA

Search for more papers by this author
Rakesh Sindhi

Rakesh Sindhi

Department of Surgery, Hillman Center for Pediatric Transplantation and Thomas E. Starzl Transplantation Institute, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA

Search for more papers by this author
Amit Tevar

Amit Tevar

Department of Surgery, Hillman Center for Pediatric Transplantation and Thomas E. Starzl Transplantation Institute, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA

Search for more papers by this author
Michael L. Moritz

Michael L. Moritz

Division of Nephrology, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA

Search for more papers by this author
Abhinav Humar

Abhinav Humar

Department of Surgery, Hillman Center for Pediatric Transplantation and Thomas E. Starzl Transplantation Institute, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA

Search for more papers by this author
George Mazariegos

George Mazariegos

Department of Surgery, Hillman Center for Pediatric Transplantation and Thomas E. Starzl Transplantation Institute, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA

Search for more papers by this author
Armando Ganoza

Corresponding Author

Armando Ganoza

Department of Surgery, Hillman Center for Pediatric Transplantation and Thomas E. Starzl Transplantation Institute, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA

Correspondence

Armando Ganoza, Department of Surgery, Hillman Center for Pediatric Transplantation and Thomas E. Starzl Transplantation Institute, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.

Email: [email protected]

Search for more papers by this author
First published: 02 April 2024

Abstract

Background

There is limited data in the literature about pediatric kidney transplant (KT) following gut transplant (GT). The purpose of this study is to highlight the technical challenges and outcomes of KT in pediatric gut recipients who developed kidney failure (KF).

Methods

A retrospective single-center study of pediatric GT recipients from January 2000 to December 2019 was performed. In total, 14 (7%) out of 206 pediatric GT recipients developed KF and were listed for KT. Ten patients underwent kidney after gut transplant (KAGT), three patients underwent simultaneous kidney and re-do gut transplant (SKAGT), and one patient died on the KT waitlist.

Results

1-, 5-, and 10-year kidney graft survival was 100%, 91%, and 78%, respectively. 1-, 5-, and 10-year GT graft survival was 100%, 77%, and 77%, respectively. 1-, 5-, and 10-year patient survival was 100%, 91%, and 91%, respectively.

Conclusion

Despite the technical complexity, KAGT and SKAGT for pediatric GT recipients that develop KF can be performed with favorable outcomes.

CONFLICT OF INTEREST STATEMENT

The authors of this manuscript have no conflicts of interest to disclose as described by the Pediatric Transplantation journal.

DATA AVAILABILITY STATEMENT

The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.

The full text of this article hosted at iucr.org is unavailable due to technical difficulties.