Volume 20, Issue 6 pp. 868-870
Case Report

A paediatric case of successful non-myeloablative bone marrow transplantation after azacitidine therapy for non-Down syndrome acute megakaryoblastic leukaemia with monosomy 7

Yuhki Koga

Corresponding Author

Yuhki Koga

Department of Paediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582 Japan

Yuhki Koga, Department of Paediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan

Tel.: +81 92 642 5093

Fax: +81 92 642 5100

E-mail: [email protected]

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Utako Oba

Utako Oba

Department of Paediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582 Japan

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Wakako Kato

Wakako Kato

Department of Paediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582 Japan

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Hiroaki Ono

Hiroaki Ono

Department of Paediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582 Japan

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Kentaro Nakashima

Kentaro Nakashima

Department of Paediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582 Japan

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Hidetoshi Takada

Hidetoshi Takada

Department of Paediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582 Japan

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First published: 06 July 2016
Citations: 1

Abstract

We report a patient with non-Down syndrome AML, also known as AMKL, with monosomy 7, who was also obese and had a hearing impairment and mental retardation. Non-myeloablative bone marrow transplantation was performed successfully after the patient received less aggressive azacitidine treatment, without the usual intensive induction chemotherapy regimen for AML.

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