Volume 34, Issue 3 pp. 337-341
Case Report

Bumps in the Road: Panniculitis in Children and Adolescents Treated with Vemurafenib

Nika Finelt M.D.

Corresponding Author

Nika Finelt M.D.

Department of Dermatology, Hofstra Northwell School of Medicine, New Hyde Park, New York

Address correspondence to Nika Finelt, M.D., Department of Dermatology, Hofstra Northwell School of Medicine, 1991 Marcus Avenue, Suite 300, New Hyde Park, NY 11042, or e-mail: [email protected].Search for more papers by this author
Rishi R. Lulla M.D., M.S.

Rishi R. Lulla M.D., M.S.

Division of Pediatric Hematology, Oncology, Neuro-Oncology and Stem Cell Transplant, Feinberg School of Medicine, Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University, Chicago, Illinois

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Hector Melin-Aldana M.D.

Hector Melin-Aldana M.D.

Division of Pathology, Feinberg School of Medicine, Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University, Chicago, Illinois

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Jennifer Shuley Ruth M.D.

Jennifer Shuley Ruth M.D.

Division of Dermatology, Texas Children's Cancer Center, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas

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Frank Y. Lin M.D.

Frank Y. Lin M.D.

Division of Pediatric Hematology-Oncology, Texas Children's Cancer Center, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas

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Jack M. Su M.D.

Jack M. Su M.D.

Division of Pediatric Hematology-Oncology, Texas Children's Cancer Center, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas

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Crystal Y. Pourciau M.D., M.P.H.

Crystal Y. Pourciau M.D., M.P.H.

Division of Dermatology, Texas Children's Cancer Center, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas

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Raegan D. Hunt M.D., Ph.D.

Raegan D. Hunt M.D., Ph.D.

Division of Dermatology, Texas Children's Cancer Center, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas

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Brandi M. Kenner-Bell M.D.

Brandi M. Kenner-Bell M.D.

Division of Dermatology, Feinberg School of Medicine, Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University, Chicago, Illinois

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First published: 19 May 2017
Citations: 11

Abstract

Vemurafenib is increasingly being used to treat nonmelanoma tumors that are positive for the BRAF V600E mutation. We report three children who presented with panniculitis induced by vemurafenib while undergoing treatment for central nervous system tumors and review the literature.

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