Rui He, School of Stomatology, Hangzhou Normal University/Stomatology Department, Affiliated Hospital of Hangzhou Normal University, No. 126, Wenzhou Road, Hangzhou 310015, Zhenjiang, China.

Email: [email protected]

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Yifan Gu,

Yifan Gu

School of Stomatology, Hangzhou Normal University, Hangzhou, China

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Cheng Qian,

Cheng Qian

School of Stomatology, Hangzhou Normal University, Hangzhou, China

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Lu Yu,

Lu Yu

School of Stomatology, Hangzhou Normal University, Hangzhou, China

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Hongzhe Fang,

Hongzhe Fang

School of Stomatology, Hangzhou Normal University, Hangzhou, China

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Jintao Wang,

Jintao Wang

Center of Stomatology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China

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Peipei Wu,

Peipei Wu

Center of Stomatology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China

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Liangjun Zhong,

Liangjun Zhong

School of Stomatology, Hangzhou Normal University, Hangzhou, China

Center of Stomatology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China

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Kai Liu,

Kai Liu

Lishui University, Lishui, China

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Rui He,

Corresponding Author

Rui He

[email protected]

orcid.org/0000-0002-8314-9155

School of Stomatology, Hangzhou Normal University, Hangzhou, China

Center of Stomatology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China

Correspondence

Rui He, School of Stomatology, Hangzhou Normal University/Stomatology Department, Affiliated Hospital of Hangzhou Normal University, No. 126, Wenzhou Road, Hangzhou 310015, Zhenjiang, China.

Email: [email protected]

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First published: 26 January 2023

https://doi.org/10.1111/odi.14521

Citations: 2

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Abstract

Objectives

In order to predict the patients' prognosis with tongue squamous cell carcinoma (SCC), this study set out to develop a clinically useful and trustworthy prognostic nomogram.

Subjects and Methods

The Surveillance, Epidemiology, and End Results (SEER) Program was used to compile clinical information on patients with tongue SCC between 2010 and 2015. The likelihood of Cancer-Specific Survival (CSS) and Overall Survival (OS) for specific patients was predicted using a prognostic nomogram created with the help of the RStudio software. The nomogram's predictive ability was evaluated using the consistency index (C-index) and decision curve analysis, and the nomogram was calibrated for 1-, 2-, 3-, 5-, and 10-year CSS and OS.

Results

Patients numbering 6453were enrolled in this study. The primary cohort (3895) and validation cohort (2558) were each randomly assigned. Sex, age, tumor-node-metastasis (TNM) stage, surgery, chemotherapy, and radiation were significant risk factors for OS, whereas age, TNM stage, surgery, chemotherapy, and radiotherapy were significant risk factors for CSS. Additionally, C-index and calibration curves indicated that the prognostic nomogram prediction and the actual observation in both cohorts would be very coherent.

Conclusions

The predictive nomogram created in this study can offer patients with tongue SCC customized treatment and survival risk assessment.

Open Research

DATA AVAILABILITY STATEMENT

The data that support the findings of this study are available from the corresponding author upon reasonable request.

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Volume30, Issue2

March 2024

Pages 292-306

Prognostic nomogram for patients with tongue squamous cell carcinoma: A SEER-based study

Abstract

Objectives

Subjects and Methods

Results

Conclusions

Open Research

DATA AVAILABILITY STATEMENT

REFERENCES

Citing Literature

References

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Prognostic nomogram for patients with tongue squamous cell carcinoma: A SEER-based study

Abstract

Objectives

Subjects and Methods

Results

Conclusions

Open Research

DATA AVAILABILITY STATEMENT

REFERENCES

Citing Literature

References

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