Insomnia, poor sleep quality and perinatal suicidal risk: A systematic review and meta-analysis
Corresponding Author
Laura Palagini
Department of Experimental and Clinical Medicine, Section of Psychiatry, University of Pisa, Pisa, Italy
Correspondence
Laura Palagini, Department of Experimental and Clinical Medicine, Section of Psychiatry, University of Pisa, Pisa, Italy.
Email: [email protected]
Contribution: Conceptualization, Investigation, Writing - original draft, Methodology, Validation, Writing - review & editing
Search for more papers by this authorEnrico Cipriani
President of the Italian Section of the Marcè Society for Perinatal Psychopathology, Milan, Italy
Contribution: Methodology, Software, Formal analysis, Data curation
Search for more papers by this authorMario Miniati
Department of Experimental and Clinical Medicine, Section of Psychiatry, University of Pisa, Pisa, Italy
Contribution: Investigation, Validation, Visualization, Supervision, Writing - review & editing
Search for more papers by this authorAlessandra Bramante
President of the Italian Section of the Marcè Society for Perinatal Psychopathology, Milan, Italy
Contribution: Supervision
Search for more papers by this authorAngelo Gemignani
Department of Surgical, Medical, Molecular, and Critical Area Pathology, University of Pisa, Pisa, Italy
Contribution: Methodology, Validation, Visualization
Search for more papers by this authorPierre A. Geoffroy
Department of Psychiatry and Addiction, AP-HP, GHU Paris Nord, DMU Neurosciences, Hôpital Bichat – Claude Bernard, Paris, France
Centre ChronoS, GHU Paris – Psychiatry & Neurosciences, Paris, France
Université Paris Cité, NeuroDiderot, Inserm, Paris, France
CNRS UPR 3212, Institute for Cellular and Integrative Neurosciences, Strasbourg, France
Contribution: Writing - review & editing, Supervision
Search for more papers by this authorDieter Riemann
Department of Psychiatry and Psychotherapy, Medical Center- University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
Contribution: Methodology, Validation, Visualization, Writing - review & editing, Supervision
Search for more papers by this authorCorresponding Author
Laura Palagini
Department of Experimental and Clinical Medicine, Section of Psychiatry, University of Pisa, Pisa, Italy
Correspondence
Laura Palagini, Department of Experimental and Clinical Medicine, Section of Psychiatry, University of Pisa, Pisa, Italy.
Email: [email protected]
Contribution: Conceptualization, Investigation, Writing - original draft, Methodology, Validation, Writing - review & editing
Search for more papers by this authorEnrico Cipriani
President of the Italian Section of the Marcè Society for Perinatal Psychopathology, Milan, Italy
Contribution: Methodology, Software, Formal analysis, Data curation
Search for more papers by this authorMario Miniati
Department of Experimental and Clinical Medicine, Section of Psychiatry, University of Pisa, Pisa, Italy
Contribution: Investigation, Validation, Visualization, Supervision, Writing - review & editing
Search for more papers by this authorAlessandra Bramante
President of the Italian Section of the Marcè Society for Perinatal Psychopathology, Milan, Italy
Contribution: Supervision
Search for more papers by this authorAngelo Gemignani
Department of Surgical, Medical, Molecular, and Critical Area Pathology, University of Pisa, Pisa, Italy
Contribution: Methodology, Validation, Visualization
Search for more papers by this authorPierre A. Geoffroy
Department of Psychiatry and Addiction, AP-HP, GHU Paris Nord, DMU Neurosciences, Hôpital Bichat – Claude Bernard, Paris, France
Centre ChronoS, GHU Paris – Psychiatry & Neurosciences, Paris, France
Université Paris Cité, NeuroDiderot, Inserm, Paris, France
CNRS UPR 3212, Institute for Cellular and Integrative Neurosciences, Strasbourg, France
Contribution: Writing - review & editing, Supervision
Search for more papers by this authorDieter Riemann
Department of Psychiatry and Psychotherapy, Medical Center- University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
Contribution: Methodology, Validation, Visualization, Writing - review & editing, Supervision
Search for more papers by this authorSummary
Suicidal risk in mothers is a public health priority. Risk factors include biological, psychological and psychosocial factors. Among the biological factors, the role of sleep disturbances as potential contributors to increased suicidal risk during the peripartum period is becoming apparent. To explore this further, we conducted a systematic review following the PRISMA criteria. Currently, 10 studies have examined the role of insomnia and poor sleep quality in suicidal risk during the peripartum period and have involved 807,760 women. The data showed that disturbed sleep and poor sleep quality increase the risk of suicidal ideation in both pregnant women with and without perinatal depression. The results of the meta-analysis indicated that insomnia and poor sleep quality increase the odds of suicidal risk in pregnant women by more than threefold (OR = 3.47; 95% CI: 2.63–4.57). Specifically, the odds ratio (OR) for poor sleep quality was 3.72 (95% CI: 2.58–5.34; p < 0.001), and for insomnia symptoms, after taking into account perinatal depression, was 4.76 (95% CI: 1.83–12.34; p < 0.001). These findings emphasise the importance of assessing and addressing sleep disturbances during the peripartum period to mitigate their adverse effects on peripartum psychopathology and suicidal risk.
CONFLICT OF INTEREST STATEMENT
The authors declare no conflicts of interest.
Open Research
DATA AVAILABILITY STATEMENT
Data sharing not applicable to this article as no datasets were generated or analysed during the current study.
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