Volume 59, Issue 1 pp. 85-91

Factors influencing the switch in the use of antihypertensive medications

C.-C. Chou

Corresponding Author

C.-C. Chou

Department of Family Medicine, 1 Tri-Service General Hospital, School of Public Health, 2 National Defense Medical Center, Taipei, Taiwan, R.O.C.

Dr Chih-Chieh Chou, Department of Family Medicine, Tri-Service General Hospital, National Defense Medical Center 325, sec. 2, Cheng Gong Road, Taipei 114, Taiwan, R.O.C.
Tel.: +886 2 8792 7120
Fax: +886 2 8792 7057
Email: [email protected]Search for more papers by this author
1 M.-S. Lee

M.-S. Lee

Department of Family Medicine, 1 Tri-Service General Hospital, School of Public Health, 2 National Defense Medical Center, Taipei, Taiwan, R.O.C.

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2 C.-H. Ke

C.-H. Ke

Department of Family Medicine, 1 Tri-Service General Hospital, School of Public Health, 2 National Defense Medical Center, Taipei, Taiwan, R.O.C.

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1 M.-H. Chuang

M.-H. Chuang

Department of Family Medicine, 1 Tri-Service General Hospital, School of Public Health, 2 National Defense Medical Center, Taipei, Taiwan, R.O.C.

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1
First published: 27 January 2005
Citations: 4

Summary

The present study was undertaken to explore factors associated with observance of prescribed antihypertensive medications. Secondary data analysis utilising ambulatory claims of the Taiwan National Health Insurance involved all initially treated hypertensive patients (n = 565,048) from June 1, 1997 to June 30, 1998. The main outcome measure was the statistical analysis of factors prompting medication switch and dropout rates. The overall continuity rate was 51%. Specific continuity rates were 40% for calcium antagonists, 36% for angiotensin-converting enzyme inhibitors, 35% for beta-blockers and 29% for diuretics. Less than 30% of patients changed medications and more than 20% of patients changed clinics. The change increased the likelihood of switching medications sevenfold. Switch was minimal for calcium antagonists. Patients taking calcium antagonists were the least likely to switch medications and had the lowest dropout rate. Changing clinics was the most influential medication switch factor.

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