Sun-induced changes of stratum corneum hydration vary with age and gender in a normal Chinese population
Zhili Liu
The Center for Research on Skin Physiology, Dalian Skin Disease Hospital, Liaoning, China
Search for more papers by this authorShunpeng Song
The Center for Research on Skin Physiology, Dalian Skin Disease Hospital, Liaoning, China
Search for more papers by this authorWenhai Luo
Department of Hygiene, Binzhou Medical College, Shandong, China
Search for more papers by this authorPeter M. Elias
Department of Dermatology, Northern California Institute for Research and Education, San Francisco, CA, USA
Search for more papers by this authorMao-Qiang Man
The Center for Research on Skin Physiology, Dalian Skin Disease Hospital, Liaoning, China
Department of Dermatology, Northern California Institute for Research and Education, San Francisco, CA, USA
Search for more papers by this authorZhili Liu
The Center for Research on Skin Physiology, Dalian Skin Disease Hospital, Liaoning, China
Search for more papers by this authorShunpeng Song
The Center for Research on Skin Physiology, Dalian Skin Disease Hospital, Liaoning, China
Search for more papers by this authorWenhai Luo
Department of Hygiene, Binzhou Medical College, Shandong, China
Search for more papers by this authorPeter M. Elias
Department of Dermatology, Northern California Institute for Research and Education, San Francisco, CA, USA
Search for more papers by this authorMao-Qiang Man
The Center for Research on Skin Physiology, Dalian Skin Disease Hospital, Liaoning, China
Department of Dermatology, Northern California Institute for Research and Education, San Francisco, CA, USA
Search for more papers by this authorAbstract
Background/objectives: Previous studies have demonstrated that sun-induced alteration of epidermal permeability barrier function varies with gender and age. In the present study, we assess the stratum corneum (SC) hydration in sun-exposed males and females.
Methods: A total of 168 subjects (84 males and 84 females) aged 19–75 years were enrolled. A multifunctional skin physiology monitor was used to measure SC hydration.
Results: In comparison with non-sun exposure, sun exposure does not cause a significant change in SC hydration in either young males or young females, whereas in aged females, a significant reduction of SC hydration is seen on the forehead and the dorsal hand of sun-exposed subjects. SC hydration on the canthus of both aged males and aged females is significantly lower than that of young subjects. Additionally, SC hydration on the dorsal hand of aged females is also significantly lower as compared with young females. Sun-induced reduction of SC hydration is more evident on the dorsal hand of aged females than that of males (P<0.001). Moreover, the SC rehydration capacity is significantly lower in sun-exposed aged females than in age-matched males.
Conclusion: These results demonstrated that sun-induced changes of the SC hydration property vary with age and gender.
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