New approaches to structural and functional imaging in focal epilepsy
Jerome Engel Jr,
Massoud Akhtari, Anatol Bragin, Itzhak Fried, Jennifer A. Ogren, Richard J. Staba, Noriko Salamon, Paul M. Thompson,
Jerome Engel Jr
Departments of Neurology
Neurobiology
Psychiatry and Biobehavioral Sciences
Brain Research Institute
Search for more papers by this authorPaul M. Thompson
Departments of Neurology
Brain Research Institute
Laboratory of Neuroimaging, David Geffen School of Medicine at UCLA, Los Angeles, California, U.S.A.
Search for more papers by this authorJerome Engel Jr,
Massoud Akhtari, Anatol Bragin, Itzhak Fried, Jennifer A. Ogren, Richard J. Staba, Noriko Salamon, Paul M. Thompson,
Jerome Engel Jr
Departments of Neurology
Neurobiology
Psychiatry and Biobehavioral Sciences
Brain Research Institute
Search for more papers by this authorPaul M. Thompson
Departments of Neurology
Brain Research Institute
Laboratory of Neuroimaging, David Geffen School of Medicine at UCLA, Los Angeles, California, U.S.A.
Search for more papers by this authorAddress correspondence to Jerome Engel, Jr, MD, PhD, Department of Neurology, David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Los Angeles, CA 90095-1769, U.S.A. E-mail: [email protected]
References
- Akhtari M, Bragin A, Cohen M, Moats R, Brenker F, Lynch MD, Vinters HV, Engel J Jr. (2008) Functionalized magnetonanoparticles for MRI diagnosis and localization in epilepsy. Epilepsia 49: 1419–1430.
- Lin JJ, Salamon N, Dutton RA, Lee AD, Geaga JA, Hayashi KM, Toga AW, Engel J Jr, Thompson PM. (2005) Three-dimensional preoperative maps of hippocampal atrophy predict surgical outcomes in temporal lobe epilepsy. Neurology 65: 1094–1097.
- Lin JJ, Salamon N, Lee AD, Dutton RA, Geaga JA, Hayashi KM, Luders E, Toga AW, Engel J Jr, Thompson PM. (2007) Reduced neocortical thickness and complexity mapped in mesial temporal lobe epilepsy with hippocampal sclerosis. Cereb Cortex 17: 2007–2018.
- Ogren JA, Bragin A, Wilson CL, Hoftman GD, Lin JJ, Dutton RA, Fields TA, Toga AW, Thompson PM, Engel J Jr, Staba RJ. (2009a) Three-dimensional hippocampal atrophy maps distinguish two common temporal lobe seizure-onset patterns. Epilepsia 50: 1361–1370.
- Ogren JA, Wilson CL, Bragin A, Lin JJ, Salamon N, Dutton RA, Luders E, Fields TA, Toga AW, Thompson PM, Engel J Jr, Staba RJ. (2009b) Pathological high frequency oscillations are associated with localized hippocampal atrophy in patients with mesial temporal lobe epilepsy. Ann Neurol, in press.
- Paxinos G, Watson C. (1997) The rat brain in stereotaxic coordinates. Academic Press, San Diego, CA.
- Thompson PM, Hayashi KM, De Zubicaray GI, Janke AL, Rose SE, Semple J, Hong MS, Herman DH, Gravano D, Doddrell DM, Toga AW. (2004) Mapping hippocampal and ventricular change in Alzheimer disease. NeuroImage 22: 1754–1766.
